H
Hoi-Wah Tsoi
Researcher at Li Ka Shing Faculty of Medicine, University of Hong Kong
Publications - 47
Citations - 9021
Hoi-Wah Tsoi is an academic researcher from Li Ka Shing Faculty of Medicine, University of Hong Kong. The author has contributed to research in topics: Coronavirus & Virus. The author has an hindex of 31, co-authored 47 publications receiving 7604 citations. Previous affiliations of Hoi-Wah Tsoi include University of Hong Kong.
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Journal ArticleDOI
Severe acute respiratory syndrome coronavirus-like virus in Chinese horseshoe bats
Susanna K. P. Lau,Patrick C. Y. Woo,Kenneth S. M. Li,Yi Huang,Hoi-Wah Tsoi,Beatrice H.L. Wong,Samson S. Y. Wong,Suet Yi Leung,Kwok-Hung Chan,Kwok-Yung Yuen +9 more
TL;DR: In a surveillance study for CoV in noncaged animals from the wild areas of the Hong Kong Special Administration Region, a CoV closely related to SARS-CoV is identified from 23 (39%) of 59 anal swabs of wild Chinese horseshoe bats by using RT-PCR and the presence of a 29-bp insertion in ORF 8 of bat-SARS- coV genome suggests that it has a common ancestor with civet SARS -CoV.
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Characterization and Complete Genome Sequence of a Novel Coronavirus, Coronavirus HKU1, from Patients with Pneumonia
Patrick C. Y. Woo,Susanna K. P. Lau,Chung-Ming Chu,Kwok-Hung Chan,Hoi-Wah Tsoi,Yi Huang,Beatrice H.L. Wong,Rosana W.S. Poon,James J. Cai,Wei-Kwang Luk,Leo L.M. Poon,Samson S. Y. Wong,Yi Guan,J. S. Malik Peiris,Kwok-Yung Yuen +14 more
TL;DR: The data support the existence of a novel group 2 coronavirus associated with pneumonia in humans, CoV-HKU1, from a 71-year-old man with pneumonia who had just returned from Shenzhen, China.
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Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens.
Jasper Fuk-Woo Chan,Cyril C. Y. Yip,Kelvin K. W. To,Tommy H. C. Tang,Sally Cheuk-Ying Wong,Kit-Hang Leung,Agnes Yim Fong Fung,Anthony Chin-Ki Ng,Zijiao Zou,Hoi-Wah Tsoi,Garnet K. Y. Choi,Anthony Raymond Tam,Vincent C.C. Cheng,Kwok-Hung Chan,Kwok-Hung Chan,Owen Tak-Yin Tsang,Kwok-Yung Yuen +16 more
TL;DR: Three novel real-time reverse transcription-PCR assays targeting the RNA-dependent RNA polymerase (RdRp)/helicase (Hel), spike (S), and nucleocapsid (N) genes of SARS-CoV-2 with that of the reported RdRp-P2 assay, which is used in >30 European laboratories are developed and compared.
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Human infections with the emerging avian influenza A H7N9 virus from wet market poultry: clinical analysis and characterisation of viral genome
Yu Chen,Weifeng Liang,Shigui Yang,Nanping Wu,Hainv Gao,Jifang Sheng,Hangping Yao,Jianer Wo,Qiang Fang,Dawei Cui,Yongcheng Li,Xing Yao,Yun-Tao Zhang,Haibo Wu,Shufa Zheng,Hongyan Diao,Shichang Xia,Yanjun Zhang,Kwok-Hung Chan,Hoi-Wah Tsoi,Jade Lee-Lee Teng,Wenjun Song,Pui Wang,Siu-Ying Lau,Min Zheng,Jasper Fuk-Woo Chan,Kelvin K. W. To,Honglin Chen,Lanjuan Li,Kwok-Yung Yuen +29 more
TL;DR: Cross species poultry-to-person transmission of this new reassortant H7N9 virus is associated with severe pneumonia and multiorgan dysfunction in human beings and monitoring of the viral evolution and further study of disease pathogenesis will improve disease management, epidemic control, and pandemic preparedness.
Journal ArticleDOI
Coronavirus Disease 2019 (COVID-19) Re-infection by a Phylogenetically Distinct Severe Acute Respiratory Syndrome Coronavirus 2 Strain Confirmed by Whole Genome Sequencing.
Kelvin K. W. To,Kelvin K. W. To,Ivan Hung,Jonathan Daniel Ip,Allen Wing-Ho Chu,Wan-Mui Chan,Anthony Raymond Tam,Carol Ho-Yan Fong,Shuofeng Yuan,Hoi-Wah Tsoi,Anthony Chin-Ki Ng,Larry Lap-Yip Lee,Polk Wan,Eugene Yuk-Keung Tso,Wing-Kin To,Dominic N.C. Tsang,Kwok-Hung Chan,Jian-Dong Huang,Kin-Hang Kok,Vincent C.C. Cheng,Vincent C.C. Cheng,Kwok-Yung Yuen,Kwok-Yung Yuen +22 more
TL;DR: The results suggest SARS-CoV-2 may continue to circulate among the human populations despite herd immunity due to natural infection or vaccination, and further studies of patients with re-infection will shed light on protective correlates important for vaccine design.