H
Holly Delgado
Researcher at University of South Florida
Publications - 8
Citations - 6580
Holly Delgado is an academic researcher from University of South Florida. The author has contributed to research in topics: Age of onset & Randomized controlled trial. The author has an hindex of 8, co-authored 8 publications receiving 4986 citations.
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
The Parkinson Progression Marker Initiative (PPMI)
Kenneth Marek,Danna Jennings,Shirley Lasch,Andrew Siderowf,Caroline M. Tanner,Tanya Simuni,Christopher S. Coffey,Karl Kieburtz,Emily Flagg,Sohini Chowdhury,Werner Poewe,Brit Mollenhauer,Todd Sherer,Mark Frasier,Claire Meunier,Alice Rudolph,Cindy Casaceli,John Seibyl,Susan Mendick,Norbert Schuff,Ying Zhang,Arthur W. Toga,Karen Crawford,Alison Ansbach,Pasquale De Blasio,Michele Piovella,John Q. Trojanowski,Les Shaw,Andrew B. Singleton,Keith A. Hawkins,Jamie L. Eberling,David W. Russell,Laura Leary,Stewart A. Factor,Barbara Sommerfeld,Penelope Hogarth,Emily Pighetti,Karen Williams,David G. Standaert,Stephanie Guthrie,Robert A. Hauser,Holly Delgado,Joseph Jankovic,Christine Hunter,Matthew B. Stern,Baochan Tran,James B. Leverenz,Marne Baca,Sam Frank,Cathi A. Thomas,Irene H. Richard,Cheryl Deeley,Linda Rees,Fabienne Sprenger,Elisabeth Lang,Holly A. Shill,Sanja Obradov,Hubert H. Fernandez,Adrienna Winters,Daniela Berg,Katharina Gauss,Douglas Galasko,Deborah Fontaine,Zoltan Mari,Melissa Gerstenhaber,David J. Brooks,Sophie Malloy,Paolo Barone,Katia Longo,Tom Comery,Bernard Ravina,Igor D. Grachev,Kim Gallagher,Michelle Collins,Katherine Widnell,Suzanne Ostrowizki,Paulo Fontoura,F. Hoffmann La-Roche,Tony W. Ho,Johan Luthman,Marcel P. van der Brug,Alastair D. Reith,Peggy Taylor +82 more
TL;DR: The Parkinson Progression Marker Initiative (PPMI) is a comprehensive observational, international, multi-center study designed to identify PD progression biomarkers both to improve understanding of disease etiology and course and to provide crucial tools to enhance the likelihood of success of PD modifying therapeutic trials.
Journal ArticleDOI
Heterozygosity for a mutation in the parkin gene leads to later onset Parkinson disease
Tatiana Foroud,Sean K. Uniacke,L. Liu,Nathan Pankratz,Anja Rudolph,Cheryl Halter,Clifford W. Shults,Karen Marder,P. M. Conneally,William C. Nichols,Lawrence I. Golbe,William C. Koller,Kelly E. Lyons,Frederick J. Marshall,David Oakes,Aileen Shinaman,Eric Siemers,Joanne Wojcieszek,Joann Belden,Julie H. Carter,Richard Camicioli,Pamela Andrews,Magali Fernandez,Jean P. Hubble,Carson Reider,Ali H. Rajput,Alex Rajput,Theresa Shirley,Michael Panisset,Jean Hall,Tilak Mendis,David Grimes,Peggy Gray,Carmen Serrano Ramos,Sandra Roque,Stephen G. Reich,Becky Dunlop,Robert A. Hauser,Juan Sanchez-Ramos,Theresa A. Zesiewicz,Holly Delgado,Joseph H. Friedman,Hubert H. Fernandez,Margaret C. Lannon,Lauren Seeberger,Christopher F. O'Brien,Deborah Judd,Lawrence Elmer,Kathy Davis,Deborah Fontaine,Ronald F. Pfeiffer,Brenda Pfeiffer,Michael J. Aminoff,Mariann DiMinno,Daniel D. Truong,Mayank Pathak,Anhoa Tran,Robert L. Rodnitzky,Judith Dobson,Rajesh Pahwa,Stephanie Thomas,Danna Jennings,Kenneth Marek,Susan Mendick,Juliette Harris,William J. Weiner,Roger Kurlan,Debra Berry,Peter A. LeWitt,Maryan DeAngelis,Paul J. Tuite,Robyn Schacherer,W.R. Wayne Martin,Marguerite Wieler,Bala V. Manyam,Patricia Simpson,John M. Bertoni,Carolyn Peterson,Mark Forrest Gordon,Joanna Hamann,Joseph Jankovic,Christine Hunter,Stewart A. Factor,Sharon Evans,Anette Nieves,Julie So,Mark Stacy,Kelli Williamson,Francis O. Walker,Victoria Hunt,Un Jung Kang,Shirley Uy,Karen Bindauer,Jeannine Petit,David Simon,Lisa Scollins,Rachel Saunders Pullman,Karyn Boyer,Paul Gordon +98 more
TL;DR: Mutations in the parkin gene occur among individuals with PD with an older age at onset (≥60 years) who have a positive family history of the disease, and the clinical findings of parkin-positive individuals are remarkably similar to those without mutations.
Journal ArticleDOI
A randomized clinical trial of coenzyme Q10 and GPI-1485 in early Parkinson disease
Karl Kieburtz,Bernard Ravina,Bernard Ravina,Wendy R. Galpern,Barbara C. Tilley,Kathleen M. Shannon,Caroline M. Tanner,G. Frederick Wooten,Robert W. Hamill,Jacob I. Sage,Emily Kosa,Ray L. Watts,Natividad R. Stover,Rebecca McMurray,Mark F. Lew,Connie Kawai,David Coffey,Pauline LeBlanc,Julie H. Carter,Matthew Brodsky,Pamela Andrews,Andrew Siderowf,Sue Reichwein,Lisa M. Shulman,William J. Weiner,Katharine Pabst,Jeana Jaglin,Robert A. Hauser,Theresa McClain,Holly Delgado,Oksana Suchowersky,Lorelei Derwent,Jayaraman Rao,Maureen Cook,Michael J. Aminoff,Chad W. Christine,Jessie Roth,Maureen A. Leehey,Jacci Bainbridge,G. Webster Ross,Stephanie Terashita,Carlos Singer,Marian A. Perez,Anita Blenke,Brad A. Racette,Patricia Deppen,Rodger J. Elble,Charlene Young,Tracy Stewart,Kapil D. Sethi,Buff Dill,John W. Taylor,Peggy Roberge,Richard B. Dewey,Brigid Hayward,Joseph Jankovic,Christine Hunter,Frederick Wooten,Margaret F. Keller,Danna Jennings,Tammie Kelsey,W.R. Wayne Martin,Germaine McInnes,Joanne Wojcieszek,Joann Belden,Roger L. Albin,Kristine Wernette,Joseph M. Savitt,Becky Dunlop,Rajesh Pahwa,Kelly E. Lyons,Amy Parsons,John Y. Fang,Dorothy Shearon,Andrew Feigin,Margaret Marie Cox,Charles H. Adler,Marlene Lind,Burton L. Scott,Joanne Field,Martha Nance,Susan Peterson,Richard S. Burns,Lynn Marlor,I. Van Bodis-Wollner,Elizabeth Hayes,Jay S. Schneider,Stephanie Sendek,Stephen Gollomp,Gwyn Vernon,Peter A LeWitt,Maryan DeAngelis,David Simon,Linda Paul,Jay M. Gorell,Shana Krstevska,Marilyn Flewellen,Sharon McCarthy,Ryan J. Uitti,Margaret F. Turk,James H. Bower,Susan Torgrimson,Marwan N. Sabbagh,Zoran Obradov,Jorge L. Juncos,Mary Louise Musante Weeks,Hubert H. Fernandez,Gordon H. Brown,Jordan J. Elm,Paulo Guimaraes,Peng Huang,Yuko Y. Palesch,Cornelia Kamp,Aileen Shinaman,Debbie Fraser,Alicia Brocht,Susan Bennett,Chris Weaver,Debbie Baker,Beverly Olsen,Christopher G. Goetz,Janis M. Miyasaki,Susan C. Fagan,Patrick D. Mauldin +123 more
TL;DR: Coenzyme Q10 and GPI-1485 may warrant further study in Parkinson disease, although the data are inconsistent, and additional factors should be considered in the selection of agents for Phase III studies.
Journal ArticleDOI
Significant Linkage of Parkinson Disease to Chromosome 2q36-37
Nathan Pankratz,William C. Nichols,Sean K. Uniacke,Cheryl Halter,Alice Rudolph,Cliff Shults,Cliff Shults,P. Michael Conneally,Tatiana Foroud,Lawrence I. Golbe,William C. Koller,Kelly E. Lyons,Karen Marder,Frederick J. Marshall,David Oakes,Aileen Shinaman,Eric Siemers,Joanne Wojcieszek,Joann Belden,Julie H. Carter,Richard Camicioli,Pamela Andrews,Magali Fernandez,Jean P. Hubble,Carson Reider,Ali H. Rajput,Alex Rajput,Theresa Shirley,Michel Panisset,Jean Hall,Tilak Mendis,David Grimes,Peggy Gray,Carmen Serrano Ramos,Sandra Roque,Stephen G. Reich,Becky Dunlop,Robert A. Hauser,Juan Sanchez-Ramos,Theresa A. Zesiewicz,Holly Delgado,Joseph H. Friedman,Hubert H. Fernandez,Margaret C. Lannon,Lauren Seeberger,Christopher F. O'Brien,Deborah Judd,Lawrence Elmer,Kathy Davis,Deborah Fontaine,Ronald F. Pfeiffer,Brenda Pfeiffer,Michael J. Aminoff,Mariann DiMinno,Daniel D. Truong,Mayank Pathak,Anhoa Tran,Robert L. Rodnitzky,Judith Dobson,Rajesh Pahwa,Stephanie Thomas,Danna Jennings,Kenneth Marek,Susan Mendick,Juliette Harris,William J. Weiner,Roger Kurlan,Debra Berry,Peter A. LeWitt,Maryan DeAngelis,Paul J. Tuite,Robyn Schacherer,W.R. Wayne Martin,Marguerite Wieler,Bala V. Manyam,Patricia Simpson,John M. Bertoni,Carolyn Peterson,Mark Forrest Gordon,Joanna Hamann,Joseph Jankovic,Christine Hunter,Stewart A. Factor,Sharon Evans,Anette Nieves,Julie So,Mark Stacy,Kelli Williamson,Francis O. Walker,Victoria Hunt,Un Jung Kang,Shirley Uy,Karen Blindauer,Jeannine Petit,David Simon,Lisa Scollins,Rachel Saunders Pullman,Karyn Boyar,Paul Gordon,Joan Werner +99 more
TL;DR: This work has expanded the sample to include 150 families meeting the strictest diagnostic definition of verified PD, and performs analyses using only those pedigrees with the strongest family history of PD, which strongly suggests that variation in a gene on chromosome 2q36-37 contributes to PD susceptibility.