H
Hong Han
Researcher at University of Würzburg
Publications - 14
Citations - 422
Hong Han is an academic researcher from University of Würzburg. The author has contributed to research in topics: Trabecular meshwork & Extracellular matrix. The author has an hindex of 8, co-authored 12 publications receiving 373 citations.
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Journal ArticleDOI
Substrate rigidity modulates cell matrix interactions and protein expression in human trabecular meshwork cells.
TL;DR: Extracellular matrix rigidity modulates cytoskeletal structures, protein expression patterns, signal transduction, and fibronectin deposition in HTM cells, and may have significant effects on ocular outflow tract functions with implications in glaucoma.
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Lovastatin Inhibits TGF-β-Induced Myofibroblast Transdifferentiation in Human Tenon Fibroblasts
TL;DR: Lovastatin inhibits TGF-beta-induced myofibroblast transdifferentiation in human Tenon fibroblasts, most likely by interfering with Rho-signaling, and may serve to inhibit scarring after filtering glaucoma surgery.
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Elasticity-dependent modulation of TGF-β responses in human trabecular meshwork cells.
TL;DR: ECM elasticity modulates TGF-β-induced signaling and protein expression in human TM cells and promotes protein expression patterns reminiscent of patterns reported in primary open-angle glaucoma.
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Ultra-soft PDMS-based magnetoactive elastomers as dynamic cell culture substrata.
Matthias Mayer,Raman Rabindranath,Juliane Börner,Eva Hörner,Alexander Bentz,J.P. Salgado,Hong Han,Holger Böse,Jörn Probst,Mikhail Shamonin,Gareth J. Monkman,Günther Schlunck +11 more
TL;DR: This MAE system provides spatial and temporal control of substratum material characteristics and permits novel designs when used as dynamic cell culture substrata or cell culture-coated actuator in tissue engineering applications or biomedical devices.
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Extracellular matrix elasticity modulates TGF-β-induced p38 activation and myofibroblast transdifferentiation in human tenon fibroblasts.
TL;DR: In this article, the impact of extracellular matrix elasticity on TGF-β-induced signal transduction and myofibroblast transdifferentiation was examined, and the results suggest that matrix elasticities influenced TGFβ-βdependent activation of p38 signaling and subsequent my-of-ibroblasts transdifferentation.