H
Hong Hoe Koo
Researcher at Samsung Medical Center
Publications - 192
Citations - 3546
Hong Hoe Koo is an academic researcher from Samsung Medical Center. The author has contributed to research in topics: Transplantation & Hematopoietic stem cell transplantation. The author has an hindex of 26, co-authored 184 publications receiving 2991 citations. Previous affiliations of Hong Hoe Koo include Sungkyunkwan University.
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Journal ArticleDOI
Comparison of immunomodulatory properties of mesenchymal stem cells derived from adult human tissues
Keon Hee Yoo,In Keun Jang,Myoung Woo Lee,Hyo Eun Kim,Mal Sook Yang,Young-Woo Eom,Jong Eun Lee,Young-Jin Kim,Seong Kyu Yang,Hye Lim Jung,Ki Woong Sung,Cheol Woo Kim,Hong Hoe Koo +12 more
TL;DR: Findings suggest that MSCs derived from AT, CB, or WJ could be substituted for BM-MSCs for treatment of allogeneic conflicts.
Journal ArticleDOI
Gene expression profile of cytokine and growth factor during differentiation of bone marrow-derived mesenchymal stem cell.
Dong Hyun Kim,Keon Hee Yoo,Kyung-Suk Choi,Jaewon Choi,Sang Yun Choi,Sung-Eun Yang,Yoon-Sun Yang,Ho Joon Im,Kye Hyun Kim,Hye Lim Jung,Ki Woong Sung,Hong Hoe Koo +11 more
TL;DR: Using RT-PCR analysis, the expression levels of cytokines and growth factors from MSCs and their differentiated cell types, including osteoblasts, adipocytes and endothelial cells are examined to help determine future clinical applications of MSCS and their derivatives for cell therapy.
Journal ArticleDOI
Enhanced Immunosuppressive Properties of Human Mesenchymal Stem Cells Primed by Interferon-γ
Dae Seong Kim,In Keun Jang,Myoung Woo Lee,Young Jong Ko,Doo-Hoon Lee,Ji Won Lee,Ki Woong Sung,Hong Hoe Koo,Hong Hoe Koo,Keon Hee Yoo,Keon Hee Yoo +10 more
TL;DR: Infusion of MSCs primed with IFN-γ significantly reduced the symptoms of graft-versus-host disease (GVHD) in NOD-SCID mice, thereby increasing survival rate when compared with naïve MSC-infused mice.
Journal ArticleDOI
Paternal smoking, genetic polymorphisms in CYP1A1 and childhood leukemia risk
Kyoung-Mu Lee,Mary H. Ward,Sohee Han,Hyo Seop Ahn,Hyoung Jin Kang,Hyung Soo Choi,Hee Young Shin,Hong Hoe Koo,Jong Jin Seo,Ji Eun Choi,Yoon Ok Ahn,Daehee Kang +11 more
TL;DR: It is suggested that paternal smoking is a risk factor for childhood leukemia and the effect may be modified by CYP1A1 genotype.
Journal ArticleDOI
Targeting survivin overcomes drug resistance in acute lymphoblastic leukemia.
Eugene Park,Eun Ji Gang,Yao Te Hsieh,Paul Schaefer,Sanna Chae,Lars Klemm,Sandra Huantes,Mignon L. Loh,Edward M. Conway,Eun Suk Kang,Hong Hoe Koo,Wolf-Karsten Hofmann,Nora Heisterkamp,Louis M. Pelus,Ganesan Keerthivasan,John D. Crispino,Michael Kahn,Markus Müschen,Yong-Mi Kim +18 more
TL;DR: It is reported that inhibition of survivin in patient-derived ALL can eradicate leukemia, and it is demonstrated that survivin inhibition may represent a powerful approach to overcoming drug resistance and preventing relapse in patients with ALL.