Hong Liu

Bio: Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.

Highly selective C–H bond activation of N-arylbenzimidamide and divergent couplings with diazophosphonate compounds: a catalyst-controlled selective synthetic strategy for 3-phosphorylindoles and 4-phosphorylisoquinolines

Abstract: A highly efficient synthetic strategy to construct 3-phosphorylindole and 4-phosphorylisoquinoline privileged scaffolds via selective C–H bond activations of N-phenylbenzimidamide and the subsequent divergent couplings with diazophosphonate compounds was achieved successfully by altering the Rh(III)/Ru(II) catalyst systems. This protocol features excellent chemoselectivity, wide substrate tolerance and mild reaction conditions, which might find wider application in the discovery of lead compounds in the future.

Generating Microdroplet Array on Photonic Pseudo-paper for Absolute Quantification of Nucleic Acids

Abstract: Here, we propose a new platform for digital nucleic acid assay based on a microdroplet array. The hydrophilic–superhydrophobic property of the pseudopaper photonic nitrocellulose substrate is employed to divide an aqueous sample containing the target nucleic acid into hundreds of microdroplets for loop-mediated isothermal amplification (LAMP). The LAMP reaction leads to the production of fluorescent calcein. By counting the number of microdroplets that are fluorescent, the target nucleic acid (i.e., Staphylococcus aureus DNA) with the copy number ranging from 1 to 1000 can be absolutely quantified without using sophisticated microfluidic devices. The effect of fluorescence enhancement attributed to the photonic nitrocellulose can effectively amplify the detection signal and reduce the amplification time. Thus, we believe that the proposed platform for digital nucleic acid assay based on the microdroplet array is promising for rapid and cost-effective bioanalytical applications.

Top or Bottom, Assembling Modules Determine the Photocatalytic Property of the Sheetlike Nanostructured Hybrid Photocatalyst Composed with Sn3O4 and rGO (GQD)

Abstract: The outstanding visible-light photocatalytic properties of Sn3O4 nanosheets and excellent electron-trapping-ability-induced photoinduced-carrier-separation enhancement ability of zero-band rGO (reduced graphene oxide) nanosheets are well-known Therefore, integration of Sn3O4 nanosheets and rGO nanosheets to prepared hybrid nanostructures has been thought of as a general strategy for synthesis of high-performance photocatalysts However, the structural and property difference of assembling modules, such as decoration of GQDs (graphene quantum dots) on Sn3O4 nanoflakes, or distributing Sn3O4 nanoflakes on rGO nanosheets, could be the key to design high-performance Sn3O4/rGO hybrid photocatalysts Up to now, there is no literature relating to this topic Here, a simple microwave-assisted hydrothermal method has been reported for the fabrication of Sn3O4/GQD and Sn3O4/rGO sheetlike nano-heterostructured hybrid photocatalysts Two photocatalysts following a different assembling modulus appeared to have differ

Porous CuS/ZnS microspheres derived from a bimetallic metal-organic framework as efficient photocatalysts for H2 production

Abstract: In this work, porous CuS/ZnS microspheres have been successfully fabricated through a facile metal-organic framework (MOF) derived route. The preparation process involved a solvothermal method for synthesis of bimetallic MOF (Cu-Zn-MOF) and subsequently vulcanization treatment to transform into CuS/ZnS microspheres. The MOF-derived CuS/ZnS microspheres inherited the porous skeleton of the Cu-Zn-MOF precursor, which significantly enhanced the utilization of light and synchronously provided plentiful exposed catalytic active sites. The obtained CuS/ZnS microspheres exhibited excellent photocatalytic activity for hydrogen production via water splitting. The optimized CuS/ZnS photocatalyst demonstrated a H2-production rate of 310.43 μmol h−1 under visible light with an apparent quantum efficiency of 8.5% at 420 nm. Such excellent photocatalytic H2-evolution activity was ascribed to the interfacial charge transfer from the valence band of ZnS to CuS, which facilitated the efficient electron-hole separation and transportation. This study provides a strategy for the rational design of MOF-derived photocatalysts to dramatically increase H2 production efficiency.

I and i

Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

The chemistry of two-dimensional layered transition metal dichalcogenide nanosheets

Abstract: Ultrathin two-dimensional nanosheets of layered transition metal dichalcogenides (TMDs) are fundamentally and technologically intriguing. In contrast to the graphene sheet, they are chemically versatile. Mono- or few-layered TMDs - obtained either through exfoliation of bulk materials or bottom-up syntheses - are direct-gap semiconductors whose bandgap energy, as well as carrier type (n- or p-type), varies between compounds depending on their composition, structure and dimensionality. In this Review, we describe how the tunable electronic structure of TMDs makes them attractive for a variety of applications. They have been investigated as chemically active electrocatalysts for hydrogen evolution and hydrosulfurization, as well as electrically active materials in opto-electronics. Their morphologies and properties are also useful for energy storage applications such as electrodes for Li-ion batteries and supercapacitors.