scispace - formally typeset
Search or ask a question
Author

Hong Liu

Other affiliations: Shanghai University, Guangzhou University, University of Jinan  ...read more
Bio: Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.


Papers
More filters
Journal ArticleDOI
TL;DR: The obtained piezoresistive and unsymmetrical tactile sensor realized a four-dimensional resolution, including a three-dimensional space and a fourth dimension of timeline, which enables future applications of human-machine interactions.
Abstract: Flexible and piezoresistive electronic skins (E-skins) with high spatial resolution are highly desired in artificial intelligence and human–machine interactions. In this study, a simple method is d...

21 citations

Journal ArticleDOI
TL;DR: Two kinds of TiO(2) nanobelts were prepared from commercial P-25 powders via an alkaline hydrothermal method with and without an acid etching process to observe electrocatalytic activities in the oxidation of nucleobases and the enhanced activity of the CTN-based electrode towards purine nucleobase oxidation was ascribed to the large specific surface area and anatase structures.
Abstract: Two kinds of TiO2 nanobelts were prepared from commercial P-25 powders via an alkaline hydrothermal method with and without an acid etching process. The uncauterized nanobelts (TNs) exhibited a smooth surface, and mixed phases of anatase and TiO2 (B), whereas the cauterized ones (CTNs) displayed a rough surface and a pure anatase structure. TNs and CTNs were then deposited onto a glassy carbon electrode (GCE) surface with a conductive adhesive (CA), and the resulting chemically modified electrodes exhibited electrocatalytic activities in the oxidation of nucleobases in a 0.1 M phosphate buffer solution (PBS) at pH 7.4. For guanine and adenine, well-defined oxidation peaks were observed in voltammetric measurements at about +0.62 and +0.89 V, respectively, at a potential sweep rate of 100 mV s−1, whereas for cytosine, uracil and thymine, the voltammetric features were not obvious. The average surface coverages (Γ) of guanine and adenine on the CTNs/CA/GCE electrode were estimated to be 4.75 × 10−10 and 7.44 × 10−10 mol cm−2, respectively, which were about twice those at the TNs/CA/GCE electrode. The enhanced activity of the CTN-based electrode towards purine nucleobase oxidation was ascribed to the large specific surface area and anatase structures with enhanced (001) facets of the CTN that facilitated adsorption of the analytes onto the electrode surface and charge transport through the electrode surface layer.

21 citations

Journal ArticleDOI
TL;DR: Light is cast on binding mechanism between EGFR and its inhibitors, which provides new hints for de novo design of new EGFR inhibitors with observable structural diversity and demonstrates that it is possible to include different kinds of inhibitors with measurable structural diversity into one 3D-QSAR study.

21 citations

Journal ArticleDOI
TL;DR: The PEGylated Au DENPs-RGD can be used as targeted nanoprobes with good biocompatibility for targeted CT imaging and diagnosis of integrin-positive tumors.

21 citations

Journal ArticleDOI
TL;DR: The N-heterocyclic carbene (NHC)-catalyzed [3+3] annulation of challenging esters with methyl ketoimines for the highly enantioselective synthesis of intriguing δ-lactams featuring various substituent patterns is disclosed.
Abstract: Herein, we disclose the N-heterocyclic carbene (NHC)-catalyzed [3+3] annulation of challenging esters with methyl ketoimines for the highly enantioselective synthesis of intriguing δ-lactams featuring various substituent patterns. The annulation occurs under mild conditions and offers good tolerance, good yields and excellent enantioselectivities. The six-membered heterocyclic products are valuable for the synthesis of bioactive molecules.

21 citations


Cited by
More filters
Journal ArticleDOI

[...]

08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Journal ArticleDOI
TL;DR: This Review describes how the tunable electronic structure of TMDs makes them attractive for a variety of applications, as well as electrically active materials in opto-electronics.
Abstract: Ultrathin two-dimensional nanosheets of layered transition metal dichalcogenides (TMDs) are fundamentally and technologically intriguing. In contrast to the graphene sheet, they are chemically versatile. Mono- or few-layered TMDs - obtained either through exfoliation of bulk materials or bottom-up syntheses - are direct-gap semiconductors whose bandgap energy, as well as carrier type (n- or p-type), varies between compounds depending on their composition, structure and dimensionality. In this Review, we describe how the tunable electronic structure of TMDs makes them attractive for a variety of applications. They have been investigated as chemically active electrocatalysts for hydrogen evolution and hydrosulfurization, as well as electrically active materials in opto-electronics. Their morphologies and properties are also useful for energy storage applications such as electrodes for Li-ion batteries and supercapacitors.

7,903 citations