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Hong Liu

Researcher at Shandong University

Publications -  2349
Citations -  79103

Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.

Papers
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Hydroxyapatite nanowires modified polylactic acid membrane plays barrier/osteoinduction dual roles and promotes bone regeneration in a rat mandible defect model.

Jing Han, +8 more
- 01 Dec 2018 - 
TL;DR: A new kind of hydroxyapatite (HAp) nanowires modified polylactic acid (PLA) membrane is introduced to achieve barrier/osteoinduction dual functions and would be a promising biomaterial in tissue engineering for bone regeneration due to its barrier and osteoinductive dual functions.
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Discovery of novel dual-action antidiabetic agents that inhibit glycogen phosphorylase and activate glucokinase.

Lei Zhang, +7 more
- 01 Dec 2012 - 
TL;DR: Dual-target-directed agents simultaneously inhibiting glycogen phosphorylase and activating glucokinase could decelerate the inflow of glucose from glycogenolysis and accelerate the outflow of glucose in the liver, therefore allow for a better control over hyperglycaemia in a synergetic manner.
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One-pot, large-scale synthesis of Nickel(II) complexes derived from 2-[N-(alpha-picolyl)amino]benzophenone (PABP) and alpha- or beta-amino acids.

Guanghui Deng, +4 more
- 19 Oct 2007 - 
TL;DR: A one-pot, large-scale procedure for preparing the Belokon-Soloshonok nucleophilic glycine equivalent 2-[N-(alpha-picolyl)amino]benzophenone (PABP) derived Ni(II) complex [GlyNi( II)PABP] is described.
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Synthesis and Anti-HIV-1 Activity Evaluation for Novel 3a,6a-Dihydro-1H-pyrrolo[3,4-c]pyrazole-4,6-dione Derivatives.

Guan-Nan Liu, +7 more
- 08 Sep 2016 - 
TL;DR: 35 novel compounds with improved biological activities against HIV-1 are designed using the recently disclosed 1-[2-(4-fluorophenyl)ethyl]-pyrrole-2,5-dione scaffolds to design 35 novel compounds that have potential as lead compounds for further optimization into clinical anti-HIV-1 agents.
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Design, Synthesis, and Biological Evaluation of Novel Tetrahydroprotoberberine Derivatives (THPBs) as Selective α1A-Adrenoceptor Antagonists

Diliang Guo, +15 more
- 12 Oct 2016 - 
TL;DR: Results of preliminary safety studies (acute toxicity and hERG inhibition) and pharmacokinetics studies indicated the potential druggability for compound (S)-27 which is a promising lead for the development of selective α1A-AR antagonists for the treatment of BPH.