H
Hong Liu
Researcher at Shandong University
Publications - 2349
Citations - 79103
Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Chemistry. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.
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Journal ArticleDOI
Structure-based design of antiviral drug candidates targeting the SARS-CoV-2 main protease.
Wenhao Dai,Wenhao Dai,Bing Zhang,Xia Ming Jiang,Haixia Su,Jian Li,Jian Li,Yao Zhao,Xiong Xie,Zhenming Jin,Jingjing Peng,Fengjiang Liu,Chunpu Li,You Li,Fang Bai,Haofeng Wang,Xi Cheng,Xiaobo Cen,Shulei Hu,Xiuna Yang,Jiang Wang,Xiang Liu,Gengfu Xiao,Hualiang Jiang,Zihe Rao,Lei Ke Zhang,Yechun Xu,Haitao Yang,Hong Liu +28 more
TL;DR: Two peptidomimetic aldehydes were designed, synthesized, and evaluated as antiviral drug candidates, and both exhibited excellent inhibitory activity and potent anti-SARS-CoV-2 infection activity.
Journal ArticleDOI
Ni3S2 nanorods/Ni foam composite electrode with low overpotential for electrocatalytic oxygen evolution
Weijia Zhou,Weijia Zhou,Weijia Zhou,Xue-Jun Wu,Xiehong Cao,Xiao Huang,Chaoliang Tan,Jian Tian,Hong Liu,Hong Liu,Jiyang Wang,Hua Zhang +11 more
TL;DR: A Ni3S2 nanorods/Ni foam composite electrode is prepared as a high-performance catalyst for the oxygen evolution reaction (OER), which exhibits excellent OER activity with a small overpotential of ∼157 mV based on the onset of catalytic current as discussed by the authors.
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Recent progress in design, synthesis, and applications of one-dimensional TiO2 nanostructured surface heterostructures: a review
TL;DR: This tutorial review introduces the characteristics of 1D TiO2 nanostructures, the design principles for the fabrication of1DTiO2NSHs, and summary of the recent progress in developing synthesis methods and applications of 1Ds in different fields is summarized.
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Self-Assembled Copper-Amino Acid Nanoparticles for in Situ Glutathione "AND" H2O2 Sequentially Triggered Chemodynamic Therapy.
Baojin Ma,Shu Wang,Feng Liu,Shan Zhang,Jiazhi Duan,Zhao Li,Ying Kong,Yuanhua Sang,Hong Liu,Hong Liu,Wenbo Bu,Wenbo Bu,Linlin Li +12 more
TL;DR: Self-assembled copper-amino acid mercaptide nanoparticles (Cu-Cys NPs) for in situ glutathione-activated and H2O2-reinforced chemodynamic therapy for drug-resistant breast cancer efficiently inhibited drug- resistant breast cancer without causing obvious systemic toxicity.
Journal ArticleDOI
Structure of the CCR5 Chemokine Receptor–HIV Entry Inhibitor Maraviroc Complex
Qiuxiang Tan,Ya Zhu,Jian Li,Z.H. Chen,Gye Won Han,Irina Kufareva,Tingting Li,Limin Ma,Gustavo Fenalti,Jing Li,Wenru Zhang,Xin Xie,Huaiyu Yang,Hualiang Jiang,Vadim Cherezov,Hong Liu,Raymond C. Stevens,Raymond C. Stevens,Raymond C. Stevens,Qiang Zhao,Beili Wu +20 more
TL;DR: The 2.7 angstrom–resolution crystal structure of human CCR5 bound to the marketed HIV drug maraviroc reveals a ligand-binding site that is distinct from the proposed major recognition sites for chemokines and the viral glycoprotein gp120, providing insights into the mechanism of allosteric inhibition of chemokine signaling and viral entry.