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Author

Hong Liu

Other affiliations: Shanghai University, Guangzhou University, University of Jinan  ...read more
Bio: Hong Liu is an academic researcher from Shandong University. The author has contributed to research in topics: Medicine & Materials science. The author has an hindex of 100, co-authored 1905 publications receiving 57561 citations. Previous affiliations of Hong Liu include Shanghai University & Guangzhou University.


Papers
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Journal ArticleDOI
TL;DR: A facile method for encapsulating a mixture of two natural fatty acids in a biocompatible, silica-based nanocapsule to achieve both stable dispersion and controllable release of drugs is reported.
Abstract: As a class of biocompatible and biodegradable phase-change materials, natural fatty acids have received considerable interest in recent years for temperature-controlled release of drugs. However, the poor dispersibility and colloidal stability of their nanoparticles under physiological conditions place a major limitation on their applications in biomedicine. Herein, we report a facile method for encapsulating a mixture of two natural fatty acids (with a eutectic melting point at 39 °C) in a biocompatible, silica-based nanocapsule to achieve both stable dispersion and controllable release of drugs. The nanocapsules have a well-defined hole in the wall to ensure easy loading of fatty acids, together with multiple types of functional components such as therapeutics and near-infrared dyes. The payloads can be released through the hole when the fatty acids are melted upon photothermal heating. The release profile can be controlled by varying the size of the hole and/or the duration of laser irradiation.

84 citations

Journal ArticleDOI
TL;DR: In this paper, a simple and fast acid oxidation treatment of carbon fibers was examined by SEM, TEM and Raman spectroscopic measurements, and the results demonstrated that porous core-shell carbon fibers might be used as effective electrode materials for the fabrication of wire-like all-carbon flexible supercapacitors with high physical flexibility and desirable electrochemical properties.
Abstract: Hierarchical porous carbon-based supercapacitors have been attracting intense attention due to their high and stable electrical double-layer capacitance that may be used for advanced technologies. In this study, porous core–shell carbon fibers were produced by a simple and fast acid oxidation treatment of carbon fibers, and the morphological and structural evolution were examined by SEM, TEM and Raman spectroscopic measurements. Detailed electrochemical characterizations showed that the resulting porous core–shell carbon fibers exhibited an excellent performance for charge storage with a specific capacitance of 98 F g−1 at 0.5 A g−1 in a 1 M H2SO4 liquid electrolyte and 20.4 F g−1 at 1 A g−1 in a H2SO4/PVA solid electrolyte, and excellent capacitance retention at ∼98.5% for the former and ∼96% for the latter over 3000 cycles. The results demonstrated that porous core–shell carbon fibers might be used as effective electrode materials for the fabrication of wire-like all-carbon flexible supercapacitors with high physical flexibility and desirable electrochemical properties.

84 citations

Journal ArticleDOI
TL;DR: In this article, ultrathin nitrogen-doped molybdenum carbide nanosheets (N-Mo2C NSs) are used as a versatile support to stabilize Ru single atoms (SAs) sites via the anti-Ostwald ripening.
Abstract: The irreversible sintering of supported ruthenium (Ru) catalyst in the preparation process has seriously affected its hydrogen evolution reaction (HER) activity and stability. Herein, ultrathin nitrogen-doped molybdenum carbide nanosheets (N-Mo2C NSs) is used as a versatile support to stabilize Ru single atoms (SAs) sites via the anti-Ostwald ripening. Ru SAs are dispersed into the N-Mo2C NSs matrix via the strong bonding between the Ru atoms and Mo2C NSs regulated by N doping. The atomic isolated Ru SAs are confirmed by spherical aberration correction transmission electron microscopy (AC HAADF-STEM) and X-ray absorption fine structure (XAFS) measurements. Ru SAs/N-Mo2C NSs exhibits outstanding HER performance, with a small overpotential of 43 mV at 10 mA/cm2, and robust catalytic stability in 1.0 M KOH. Importantly, Ru SAs/N-Mo2C NSs possesses a higher mass activity of 6.44 A/mgRu than that of 20 wt% Pt/C (0.91 A/mgPt) at the overpotential of 100 mV. Theoretical calculations further reveal that the high HER activity of Ru SAs/N-Mo2C NSs is derived from the synergistically accelerated the dissociation of H2O and the optimized H adsorption strength in Mo-Ru interface. This result provides a new direction for the rational designing monatomic electrocatalysts for HER via support interaction effect.

82 citations

Journal ArticleDOI
22 Jan 2019-ACS Nano
TL;DR: The advanced heart-on-a-chip system with the feature of microphysiological visuality has been developed for integrated cell monitoring and drug testing and this anisotropic inverse opal-derived biohybrid actuator could be widely applied in biomedical engineering.
Abstract: Biohybrid actuators composed of living tissues and artificial materials have attracted increasing interest in recent years because of their extraordinary function of dynamically sensing and interacting with complex bioelectrical signals. Here, a compound biohybrid actuator with self-driven actuation and self-reported feedback is designed based on an anisotropic inverse opal substrate with periodical elliptical macropores and a hydrogel filling. The benefit of the anisotropic surface topography and high biocompatibility of the hydrogel is that the planted cardiomyocytes could be induced into a highly ordered alignment with recovering autonomic beating ability on the elastic substrate. Because of the cell elongation and contraction during cardiomyocyte beating, the anisotropic inverse opal substrates undergo a synchronous cycle of deformation actuations, which can be reported as corresponding shifts of their photonic band gaps and structural colors. These self-driven biohybrid actuators could be used as ele...

82 citations

Journal ArticleDOI
TL;DR: The strain Pseudomonas putida ZWL73, which metabolizes 4-chloronitrobenzene by a partial-reductive pathway, was inoculated into lab-scale 4CNB-contaminated soil for bioaugmentation purposes and showed changes of diversity in dominant populations of intrinsic soil microbiota.

81 citations


Cited by
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Journal ArticleDOI

[...]

08 Dec 2001-BMJ
TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality. Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …

33,785 citations

28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

18,940 citations

Journal ArticleDOI
TL;DR: This Review describes how the tunable electronic structure of TMDs makes them attractive for a variety of applications, as well as electrically active materials in opto-electronics.
Abstract: Ultrathin two-dimensional nanosheets of layered transition metal dichalcogenides (TMDs) are fundamentally and technologically intriguing. In contrast to the graphene sheet, they are chemically versatile. Mono- or few-layered TMDs - obtained either through exfoliation of bulk materials or bottom-up syntheses - are direct-gap semiconductors whose bandgap energy, as well as carrier type (n- or p-type), varies between compounds depending on their composition, structure and dimensionality. In this Review, we describe how the tunable electronic structure of TMDs makes them attractive for a variety of applications. They have been investigated as chemically active electrocatalysts for hydrogen evolution and hydrosulfurization, as well as electrically active materials in opto-electronics. Their morphologies and properties are also useful for energy storage applications such as electrodes for Li-ion batteries and supercapacitors.

7,903 citations