Author
Hongbin Tu
Bio: Hongbin Tu is an academic researcher from Donghua University. The author has contributed to research in topics: Fiber & Nanofiber. The author has an hindex of 5, co-authored 7 publications receiving 214 citations.
Topics: Fiber, Nanofiber, Composite number, Electrospinning, Spinning
Papers
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TL;DR: Electrospun GT/PCL and other similar natural-synthetic hybrid systems in constructing tissue-engineered scaffolds may offer a facile and effective approach to achieve finer and compositionally homogeneous hybrid nanofibers for effective applications.
102 citations
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TL;DR: The results suggest that crosslinking with the 0.5% GP in PBS could yield CTS nanofibers with improved wet stability in nanofiber structure and optimized mechanical and biological performances.
80 citations
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TL;DR: In this paper, a stable jet electrospinning technique is proposed for the fabrication of ultrafine fibers in micro/nano-scale fineness. But, it is still a huge technological challenge in achieving aligned fibers and arrays due to the inherent chaotic motion of an electro-spinning jet.
Abstract: Electrospinning has emerged as an attractive technique for the fabrication of ultrafine fibers in micro-/nano-scale fineness. However, it is still a huge technological challenge in achieving aligned fibers and arrays due to the inherent chaotic motion of an electrospinning jet. We report herein a novel spinning approach termed stable jet electrospinning to offer a facile solution to the noted issue. It involves judiciously using an ultrahigh molecular weight poly(ethylene oxide) to formulate the viscoelasticity of a spinning dope such that a very long and stable jet can be formed during electrospinning. This consequently allows for readily collecting and fabricating individual fibers, multi-filament yarns, well-aligned unidirectional fiber arrays in a large area, and ordered fiber patterns by controlling fiber placement. Our approach could thus open up the possibility of achieving continuous aligned ultrafine fibers and structures in a straightforward and scalable fashion, suitable for a variety of practical applications.
50 citations
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22 Jan 2014
TL;DR: In this paper, a preparation method of oriented shell-core structural superfine composite fiber is proposed, which comprises the steps of dissolving biological activity natural macromolecule in a solvent, and stirring to obtain a shell spinning solution; dissolving polylactic acid (PLLA) and polyoxyethylene (PEO) in the solvent.
Abstract: The invention relates to a preparation method of oriented shell-core structural superfine composite fiber The preparation method comprises the steps of dissolving biological activity natural macromolecule in a solvent, and stirring to obtain a shell spinning solution; dissolving polylactic acid (PLLA) and polyoxyethylene (PEO) in the solvent, and stirring to obtain a core spinning solution; and respectively extracting the shell spinning solution and the core spinning solution, jetting and stably and coaxially electrospining to obtain the shell-core structural superfine composite fiber The shell-core structural superfine composite fiber, which effectively combines synthetic materials and natural materials, integrates mechanical performance and biocompatibility of fiber and can prepare the shell-core structural superfine composite fiber which is relatively high in orientation degree in large scale as conventional mechanical spinning; and the oriented superfine composite fiber prepared by the preparation method has application prospect in repairing tendon, ligament and other tissues
12 citations
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27 Jun 2012
TL;DR: In this paper, a preparation method of an NiO/gamma-Al2O3 composite ceramic nanofiber was proposed, and the method consisted of mixing and stirring an aluminum salt with a solvent, adding a nickel salt into the aluminum salt solution, and stirring them fully so as to obtain an aluminium salt/nickel salt mixed solution.
Abstract: The invention relates to a preparation method of an NiO/gamma-Al2O3 composite ceramic nanofiber, and the method comprises: (1) mixing and stirring an aluminum salt with a solvent so as to obtain an aluminum salt solution, adding a nickel salt into the aluminum salt solution, and stirring them fully so as to obtain an aluminum salt/nickel salt mixed solution; (2) first adding a spinnable polymer into the solvent, and adding the obtained solution into the aluminum salt/nickel salt mixed solution, thus obtaining an aluminum salt/nickel salt/spinnable polymer mixed spinning solution; (3) subjecting the mixed spinning solution to electrostatic spinning, thus obtaining a precursor composite nanofiber; and (4) calcinating the precursor composite nanofiber so as to obtain the NiO/gamma-Al2O3 composite ceramic nanofiber. The method of the invention utilizes the traditional electrostatic spinning technology for preparing an inorganic nanofiber indirectly, and the fiber has uniform diameter distribution, high length-diameter ratio, and good flexibility. And the method has simple and practicable process, as well as high success rate.
8 citations
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TL;DR: The potential for using MNA-loaded PCL/gelatin electrospun membranes as anti-infective GTR/GBR membranes to optimize clinical application of GTR-GBR strategies is indicated.
303 citations
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TL;DR: Latest developments in terms of constituents, fabrication technologies, structural, and bioactive properties of these materials that may represent an effective solution for tissue engineering materials, making them a realistic clinical alternative in the near future are covered.
267 citations
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TL;DR: How the 3D printing technology can contribute to the improvement of traditional electrospinning technology for the fabrication of 3D electrospun nanofiber materials as drug delivery devices/implants, scaffolds or living tissue constructs is emphasized.
259 citations
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TL;DR: The design of electrospun polymer/protein nanofiber membranes was effective for guided bone regeneration and the in vitro osteogenesis characterizations, alizarin red in normal medium and osteogenesis medium, indicated that the nanofibers could promote bone formation.
256 citations
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TL;DR: Natural polymers, synthetic polymers and their blends are all introduced and despite there still being complaints about polymer membranes, these problems will undoubtedly be conquered and biodegradable polymers will have more applications in GTR and GBR.
Abstract: Polymer membranes have been widely used in guided tissue regeneration (GTR) and guided bone regeneration (GBR). In this review, various commercially available membranes are described. Much attention is paid to the recent development of biodegradable polymers applied in GTR and GBR, and the important issues of biodegradable polymeric membranes, including their classification, latest experimental research and clinical applications, as well as their main challenges are addressed. Herein, natural polymers, synthetic polymers and their blends are all introduced. Pure polymer membranes are biodegradable and biocompatible, but they lack special properties such as antibacterial properties, osteoconductivity, and thus polymer membranes loaded with functional materials such as antibacterial agents and growth factors show many more advantages and have also been introduced in this review. Despite there still being complaints about polymer membranes, such as their low mechanical properties, uncontrollable degradation speed and some other drawbacks, these problems will undoubtedly be conquered and biodegradable polymers will have more applications in GTR and GBR.
229 citations