H
Hongjie Zhang
Researcher at Nanjing University
Publications - 12
Citations - 4528
Hongjie Zhang is an academic researcher from Nanjing University. The author has contributed to research in topics: Work related & Enteroendocrine cell. The author has an hindex of 7, co-authored 12 publications receiving 4171 citations. Previous affiliations of Hongjie Zhang include Nanjing Medical University.
Papers
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Journal ArticleDOI
Characterization of microRNAs in serum: a novel class of biomarkers for diagnosis of cancer and other diseases
Xi Chen,Yi Ba,Lijia Ma,Lijia Ma,Xing Cai,Yuan Yin,Kehui Wang,Jigang Guo,Yujing Zhang,Jiangning Chen,Xing Guo,Qibin Li,Qibin Li,Xiaoying Li,Wenjing Wang,Yan Zhang,Jin Wang,Xueyuan Jiang,Yang Xiang,Chen Xu,Pingping Zheng,Juanbin Zhang,Ruiqiang Li,Hongjie Zhang,Xiaobin Shang,Ting Gong,Guang Ning,Jun Wang,Jun Wang,Ke Zen,Junfeng Zhang,Chen-Yu Zhang +31 more
TL;DR: It is demonstrated that miRNAs are present in the serum and plasma of humans and other animals such as mice, rats, bovine fetuses, calves, and horses, and can serve as potential biomarkers for the detection of various cancers and other diseases.
Journal ArticleDOI
Differential expression of microRNAs in mouse liver under aberrant energy metabolic status
Shengjie Li,Xi Chen,Hongjie Zhang,Xiangying Liang,Yang Xiang,Chaohui Yu,Ke Zen,Youming Li,Chen-Yu Zhang +8 more
TL;DR: An important role of miRNAs in hepatic energy metabolism is suggested and the participation of mi RNAs in the pathophysiological processes of NAFLD is implicate.
Journal ArticleDOI
PGC-1α Is a Key Regulator of Glucose-Induced Proliferation and Migration in Vascular Smooth Muscle Cells
Lingyun Zhu,Guoxun Sun,Hongjie Zhang,Hongjie Zhang,Yan-Yan Zhang,Xi Chen,Xiaohong Jiang,Xueyuan Jiang,Stefan Krauss,Junfeng Zhang,Yang Xiang,Chen-Yu Zhang +11 more
TL;DR: Results indicate that P GC-1α is a key regulator of high glucose-induced proliferation and migration in VSMCs, and suggest that elevation of PGC-1 α in VS MC could be a useful strategy in preventing the development of diabetic atherosclerosis.
Journal ArticleDOI
microRNA-200b and microRNA-200c promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs
Yi Pan,Hongwei Liang,Weixu Chen,Hongjie Zhang,Nan Wang,Feng Wang,Suyang Zhang,Yanqing Liu,Chihao Zhao,Xin Yan,Junfeng Zhang,Chen-Yu Zhang,Hongwei Gu,Ke Zen,Xi Chen +14 more
TL;DR: It is reported that miR-200b/c can promote colorectal cancer cell proliferation via targeting the reversion-inducing cysteine-rich protein with Kazal motifs (RECK) through inhibiting RECK expression and subsequently triggering SKP2 elevation and p27Kip1 degradation.
Patent
Micrornas in serum/blood plasma and their uses
TL;DR: In this paper, a combination and a biochip was proposed for diagnosing diseases in human serum/blood plasma, which can be used for evaluating physiological state and/or pathological state of subjects.