Hongqi Li

TL;DR: How calpain activity is regulated in cells is still unclear, but the calpains ostensibly participate in a variety of cellular processes including remodeling of cytoskeletal/membrane attachments, different signal transduction pathways, and apoptosis.

TL;DR: Ionic-strength-induced dissociation of the two subunits in the autolyzed calpains indicates that salt bridges have an important, possibly indirect, role in the domain IV/domain VI interaction.

TL;DR: This is the first report of two isoforms of m-calpain in a single species and Sequencing tryptic peptides indicated that the amino acids sequence of trout calpastatin shares little homology with the amino acid sequences of mammalian calpastatins.

TL;DR: It is shown that at low ionic strength, calpastatin from skeletal muscle extracts binds quantitatively to an immunoaffinity column made by coupling a monoclonal antibody to the C-terminal end of calPastatin (epitope between amino acids 707 and 786) to agarose; the bound cal Pastatin can be eluted at pH 2.5.

TL;DR: Wang et al. as mentioned in this paper explored the prevalence and characteristics of MetS defined by different criteria in the Chinese population and used multivariable logistic regression to identify factors associated with MetS.