Hongzhou Lu

TL;DR: A new-type coronav virus, tentatively named by World Health Organization as the 2019-new coronavirus (2019-nCoV), had caused this outbreak in Wuhan city, Hubei Province, China, it was announced today.

TL;DR: Patients with fever and/or cough and with conspicuous ground-glass opacity lesions in the peripheral and posterior lungs on CT images, combined with normal or decreased white blood cells and a history of epidemic exposure, are highly suspected of having 2019 Novel Coronavirus (2019-nCoV) pneumonia.

TL;DR: Three general methods, which include existing broad-spectrum antiviral drugs using standard assays, screening of a chemical library containing many existing compounds or databases, and the redevelopment of new specific drugs based on the genome and biophysical understanding of individual coronaviruses, are used to discover the potential antiviral treatment of human pathogen coronavirus.

TL;DR: Clinical data from 326 cases suggest that T cell depletion and cytokine bursts are associated with a worse prognosis, and genomic sequences from 112 patients with confirmed SARS-CoV-2 virus showed two clades with similar virulence and clinical outcome.

TL;DR: Multiple organ dysfunction and impaired immune function were the typical characteristics of patients with severe or critical illness and there was a significant difference in the use of angiotensin-converting enzyme inhibitors/angiotens in II receptor blockers among patients with different severities of disease.