Hope I. Needs

TL;DR: Analysis of expression of excitatory and inhibitory neurotransmitter receptor subunits and synaptic scaffolding proteins in the hippocampus and temporal lobe and compared these changes with alterations in network activity at specific timepoints during epileptogenesis gives new insight into the mechanisms underpinning epilepsy.

TL;DR: In this paper, a review of the cell biology of GluK2-containing KARs and GluA2containing AMPARs is presented, and the role of kARs in regulating AMPAR surface expression and plasticity, and relevance of this to epilepsy.

TL;DR: An adaptation of an assay system, established previously to monitor mitochondrial import into isolated yeast mitochondria, to quantitatively monitor mitochondria import inside mammalian cells is reported, enabling detailed mechanistic examination of the transport process in live cells.

TL;DR: A mitochondrial import rescue mechanism involving intercellular mitochondrial transport through tunneling nanotubes (TNTs) was proposed in this paper , where the import of healthy mitochondria and jettisoning of those with jammed import sites was considered.

TL;DR: In this article, the authors focus on how the processes of mitochondrial protein translocation and respiratory complex assembly and function are interlinked, how they are regulated, and their importance in health and disease.