Author
Hua Chen
Bio: Hua Chen is an academic researcher from Sichuan University. The author has contributed to research in topics: Catalysis & Aryl. The author has an hindex of 10, co-authored 30 publications receiving 278 citations.
Papers
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TL;DR: A catalyst composed of [Pd(η(3)-C3H5)Cl]2 and N,N,N',N'-tetra(diphenylphosphinomethyl)pyridine-2,6-diamine (L) was found to be effective for one-pot synthesis of 2-substituted benzo[b]furans from 2-halophenols and alkynes.
68 citations
TL;DR: Achiral monophosphine TPPTS [TPPTS: P(m -C 6 H 4 SO 3 Na) 3 ]-stabilized Ru was synthesized by reduction of RuCl 3 ·3H 2 O with hydrogen in ethanol using TPPTS as the stabilizer as mentioned in this paper.
Abstract: Achiral monophosphine TPPTS [TPPTS: P( m -C 6 H 4 SO 3 Na) 3 ]-stabilized Ru was synthesized by reduction of RuCl 3 ·3H 2 O with hydrogen in ethanol using TPPTS as the stabilizer. The catalytic asymmetric hydrogenation of aromatic ketones using TPPTS-stabilized Ru modified by a chiral diamine (1 R ,2 R )-DPENDS [disodium salt of sulfonated (1 R ,2 R )-1,2-diphenyl-1,2-ethylene-diamine] was investigated in hydrophilic ionic liquid [RMIM]Ts (1-alkyl-3-methylimidazolium p -methylphenylsulfonates, R = ethyl, butyl, octyl, dodecyl, hexadecyl). Hundred percent conversion and 85.1% ee were obtained for acetophenone under optimized conditions. The resulting products can be easily separated from the catalyst immobilized in ionic liquid by simple extraction with n -hexane, and the catalyst can be reused several times without a significant loss of ee value or conversion. In particular, the addition of water can improve the catalyst performance.
38 citations
TL;DR: In this paper, an efficient, general, one-pot, three-component procedure for the preparation of 3,5-disubstituted 1H-pyrazoles via condensation of substituted aromatic aldehydes, tosylhydrazine and terminal alkynes in toluene is reported.
Abstract: An efficient, general, one-pot, three-component procedure for the preparation of 3,5-disubstituted 1H-pyrazoles via condensation of substituted aromatic aldehydes, tosylhydrazine and terminal alkynes in toluene is reported. The reaction tolerates a variety of functional groups and sterically hindered substrates to afford the desired pyrazoles in yields of 67–91%.
33 citations
TL;DR: In this paper, three Ru-η6-benzene-phosphine complexes bearing tri-(p-methoxyphenyl)phosphines, triphenylphophosphine, and tri-p-trifluoromethylphenyl) phosphine were synthesized and characterized by 31P{1H} NMR, 1H NMR and 13C{ 1H nMR and elemental analyses.
Abstract: Three Ru–η6-benzene–phosphine complexes bearing tri-(p-methoxyphenyl)phosphine, triphenylphosphine and tri-(p-trifluoromethylphenyl)phosphine were synthesized and characterized by 31P{1H} NMR, 1H NMR, 13C{1H} NMR and elemental analyses. Complex 1 was further identified by X-ray crystallography. These complexes exhibit good to excellent activities for the transfer hydrogenation of ketones in refluxing 2-propanol, and the highest turnover frequency (TOF) is up to 5940 h−1. The effect of electronic factors of these complexes on the transfer hydrogenation of ketones reveals that the catalytic activity is promoted by electron-donating phosphine and the catalyst stability is improved by electron-withdrawing phosphine. Copyright © 2011 John Wiley & Sons, Ltd.
26 citations
TL;DR: In this article, the Mizoroki-Heck reactions of aryl halides catalyzed by palladium nanoparticles generated in situ from a simple allyl palladium precursor were investigated in argon.
24 citations
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TL;DR: The concept of homogeneous supported catalysts has emerged as a useful alternative to homogeneous as well as heterogeneous catalysis, possibly combining positive aspects of both as mentioned in this paper, and designing catalysts with respect to not only their catalytic activity but also their physical-chemical properties appears to be a possible way towards sustainable chemical synthesis.
162 citations