Author
Hua Zhang
Other affiliations: Shenzhen University, Zhengzhou University, Norwegian University of Science and Technology ...read more
Bio: Hua Zhang is an academic researcher from Chinese Academy of Sciences. The author has contributed to research in topics: Medicine & Graphene. The author has an hindex of 163, co-authored 1503 publications receiving 116769 citations. Previous affiliations of Hua Zhang include Shenzhen University & Zhengzhou University.
Topics: Medicine, Graphene, Materials science, Chemistry, Catalysis
Papers published on a yearly basis
Papers
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TL;DR: In this paper, the influence of three rolling routes on the microstructure evolution and properties of AZ31 magnesium alloy sheets was investigated, and the results indicated that compared with the Route A rolled sample, the Route B and Route C rolled samples produce finer recrystallized grains and weaker basal texture due to the alternating changing direction of tensile stress and compressive stress during rolling.
62 citations
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TL;DR: A highly selective and sensitive aptamer-based “capture-release” fluorescence detection of a malarial biomarker, i.e., Plasmodium lactose dehydrogenase (pLDH) protein, using single-layer two-dimensional MoS2 nanosheets.
Abstract: We demonstrate a highly selective and sensitive aptamer-based “capture-release” fluorescence detection of a malarial biomarker, i.e., Plasmodium lactose dehydrogenase (pLDH) protein, using single-layer two-dimensional MoS2 nanosheets. The detection of the target pLDH protein utilizing the aptamer-nanosheet sensing platform is rapid and can be easily completed within 10 min. In addition, the developed biomolecular sensor is capable of detecting the target malarial biomarker in homogeneous protein solutions as well as in heterogeneous mixtures of proteins. We anticipate that the ultrathin MoS2 nanosheet-based biosensor will facilitate the further development of biomolecular nanosensors for the detection of a wide range of biomarkers for malaria and other diseases.
62 citations
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TL;DR: In this paper, Zirconium diboride reinforced carbon (ZrB2/C) composites were prepared from petroleum coke, coal tar pitch and ZrB 2 powder by hot-pressing.
62 citations
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TL;DR: A novel 3D cobalt sulfide nanoparticle-decorated nitrogen and sulfur co-doped reduced graphene oxide aerogel (NSGA), referred to as CoS/NSGA, is prepared via three sequential processes, i.e., freeze-drying, annealing, and sulfidization, exhibiting excellent electrocatalytic performance in the alkaline solution.
Abstract: A novel 3D cobalt sulfide (CoS) nanoparticle-decorated nitrogen and sulfur co-doped reduced graphene oxide aerogel (NSGA), referred to as CoS/NSGA, is prepared via three sequential processes, i.e., freeze-drying, annealing, and sulfidization. The obtained CoS/NSGA exhibits excellent electrocatalytic performance in the alkaline solution.
62 citations
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TL;DR: Phainanoids A-F (1-6), six highly modified triterpenoids with a new carbon skeleton by incorporating two unique motifs of a 4,5- and a 5,4-spirocyclic systems, were isolated from Phyllanthus hainanensis and exhibited exceptionally potent immunosuppressive activities in vitro against the proliferation of T and B lymphocytes.
Abstract: Phainanoids A–F (1–6), six highly modified triterpenoids with a new carbon skeleton by incorporating two unique motifs of a 4,5- and a 5,5-spirocyclic systems, were isolated from Phyllanthus hainanensis. Their structures with absolute configurations were determined by spectroscopic data, chemical methods, and X-ray crystallography. Compounds 1–6 exhibited exceptionally potent immunosuppressive activities in vitro against the proliferation of T and B lymphocytes. The most potent one, phainanoid F (6), showed activities against the proliferation of T cells with IC50 value of 2.04 ± 0.01 nM (positive control CsA = 14.21 ± 0.01 nM) and B cells with IC50 value of <1.60 ± 0.01 nM (CsA = 352.87 ± 0.01 nM), which is about 7 and 221 times as active as CsA, respectively. The structure–activity relationships of 1–6 are discussed.
62 citations
Cited by
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TL;DR: There is, I think, something ethereal about i —the square root of minus one, which seems an odd beast at that time—an intruder hovering on the edge of reality.
Abstract: There is, I think, something ethereal about i —the square root of minus one. I remember first hearing about it at school. It seemed an odd beast at that time—an intruder hovering on the edge of reality.
Usually familiarity dulls this sense of the bizarre, but in the case of i it was the reverse: over the years the sense of its surreal nature intensified. It seemed that it was impossible to write mathematics that described the real world in …
33,785 citations
01 May 1993
TL;DR: Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems.
Abstract: Three parallel algorithms for classical molecular dynamics are presented. The first assigns each processor a fixed subset of atoms; the second assigns each a fixed subset of inter-atomic forces to compute; the third assigns each a fixed spatial region. The algorithms are suitable for molecular dynamics models which can be difficult to parallelize efficiently—those with short-range forces where the neighbors of each atom change rapidly. They can be implemented on any distributed-memory parallel machine which allows for message-passing of data between independently executing processors. The algorithms are tested on a standard Lennard-Jones benchmark problem for system sizes ranging from 500 to 100,000,000 atoms on several parallel supercomputers--the nCUBE 2, Intel iPSC/860 and Paragon, and Cray T3D. Comparing the results to the fastest reported vectorized Cray Y-MP and C90 algorithm shows that the current generation of parallel machines is competitive with conventional vector supercomputers even for small problems. For large problems, the spatial algorithm achieves parallel efficiencies of 90% and a 1840-node Intel Paragon performs up to 165 faster than a single Cray C9O processor. Trade-offs between the three algorithms and guidelines for adapting them to more complex molecular dynamics simulations are also discussed.
29,323 citations
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28,685 citations
28 Jul 2005
TL;DR: PfPMP1)与感染红细胞、树突状组胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作�ly.
Abstract: 抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1(PfPMP1)与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用,在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员,通过启动转录不同的var基因变异体为抗原变异提供了分子基础。
18,940 citations
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TL;DR: This work reviews the historical development of Transition metal dichalcogenides, methods for preparing atomically thin layers, their electronic and optical properties, and prospects for future advances in electronics and optoelectronics.
Abstract: Single-layer metal dichalcogenides are two-dimensional semiconductors that present strong potential for electronic and sensing applications complementary to that of graphene.
13,348 citations