scispace - formally typeset
Search or ask a question
Author

Hugh Watson

Other affiliations: Aarhus University Hospital
Bio: Hugh Watson is an academic researcher from Aarhus University. The author has contributed to research in topics: Cirrhosis & Ascites. The author has an hindex of 13, co-authored 37 publications receiving 1141 citations. Previous affiliations of Hugh Watson include Aarhus University Hospital.

Papers
More filters
Journal ArticleDOI
TL;DR: Low serum sodium levels in cirrhosis are associated with severe ascites and high frequency of hepatic encephalopathy, spontaneous bacterial peritonitis, and hepatorenal syndrome.

367 citations

Journal ArticleDOI
TL;DR: The V2 receptor antagonist satavaptan improves the control of ascites and increases serum sodium in patients with cirrhosis, ascites, and hyponatremia under diuretic treatment.

189 citations

Journal ArticleDOI
TL;DR: PPIs were used by 52% of this international cirrhosis cohort during a 1‐year period and was a risk factor for developing HE and SBP, consistent with the hypothesis that PPIs may increase translocation of gut bacteria.

143 citations

Journal ArticleDOI
TL;DR: Serum sodium concentration and presence of leg edema are major factors of the impaired HRQL in patients with cirrhosis and ascites.

107 citations

Journal ArticleDOI
TL;DR: In this paper, the safety of nonselective β-blockers (NSBBs) in advanced cirrhosis has been questioned, and a large and detailed data set on worldwide non-protocol use of NSBBs in patients with ascites is presented.

95 citations


Cited by
More filters
Journal ArticleDOI
TL;DR: The panel of experts, having emphasised the importance of initiating aetiologic treatment for any degree of hepatic disease at the earliest possible stage, extended its work to all the complications of cirrhosis which had not been covered by the European Association for the Study of the Liver guidelines.

1,534 citations

Journal ArticleDOI
TL;DR: There is a clear rationale for the management of ascites in patients with cirrhosis, as successful treatment may improve outcome and symptoms, and patients with ascites should generally be considered for referral for liver transplantation.

1,476 citations

Journal ArticleDOI
TL;DR: This guidance provides a data-supported approach to risk stratification, diagnosis, and management of patients with cirrhosis and portal hypertension (PH), varices, and variceal hemorrhage (VH), and statements are based on the following.

1,397 citations

Journal ArticleDOI
TL;DR: The AASLD/EASL Practice Guideline Subcommittee on Hepatic Encephalopathy are: Jayant A. Talwalkar, Hari S. Conjeevaram, Michael Porayko, Raphael B. Merriman, Peter L. Jansen, Fabien Zoulim.

1,375 citations

Journal ArticleDOI
TL;DR: The Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia is developed as a joint venture of three societies representing specialists with a natural interest in hyponatonemia to obtain a common and holistic view.
Abstract: Hyponatraemia, defined as a serum sodium concentration !135 mmol/l, is the most common disorder of body fluid and electrolyte balance encountered in clinical practice. It can lead to a wide spectrum of clinical symptoms, from subtle to severe or even life threatening, and is associated with increased mortality, morbidity and length of hospital stay in patients presenting with a range of conditions. Despite this, the management of patients remains problematic. The prevalence of hyponatraemia in widely different conditions and the fact that hyponatraemia is managed by clinicians with a broad variety of backgrounds have fostered diverse institution- and speciality-based approaches to diagnosis and treatment. To obtain a common and holistic view, the European Society of Intensive Care Medicine (ESICM), the European Society of Endocrinology (ESE) and the European Renal Association – European Dialysis and Transplant Association (ERA–EDTA), represented by European Renal Best Practice (ERBP), have developed the Clinical Practice Guideline on the diagnostic approach and treatment of hyponatraemia as a joint venture of three societies representing specialists with a natural interest in hyponatraemia. In addition to a rigorous approach to methodology and evaluation, we were keen to ensure that the document focused on patient-important outcomes and included utility for clinicians involved in everyday practice.

879 citations