다중혈관 관상동맥 환자에서 y-문합을 이용하여 양쪽 내흉동맥만을 사용한 우회술의 조기 성적

http://experimentationlab.berkeley.edu/sites/default/files/AFMImages/butt_AFM.pdf

Force measurements with the atomic force microscope: Technique, interpretation and applications

THE forces between colloidal particles dominate the behaviour of a great variety of materials, including paints, paper, soil, clays and (in some circumstances) cells. Here we describe the use of the atomic force microscope to measure directly the force between a planar surface and an individual colloid particle. The particle, a silica sphere of radius 3.5 µm, was attached to the force sensor in the microscope and the force between the particle and the surface was measured in solutions of sodium chloride. The measurements are consistent with the double-layer theory1,2 of colloidal forces, although at very short distances there are deviations that may be attributed to hydration forces3–6 or surface roughness, and with previous studies on macroscopic systems4–6. Similar measurements should be possible for a wide range of the particulate and fibrous materials that are often encountered in industrial contexts, provided that they can be attached to the microscope probe.

Direct measurement of colloidal forces using an atomic force microscope

1: Magnetic Particles: Preparation, Properties and Applications: M. Ozaki. 2: Maghemite (gamma-Fe2O3): A Versatile Magnetic Colloidal Material C.J. Serna, M.P. Morales. 3: Dynamics of Adsorption and Oxidation of Organic Molecules on Illuminated Titanium Dioxide Particles Immersed in Water M.A. Blesa, R.J. Candal, S.A. Bilmes. 4: Colloidal Aggregation in Two-Dimensions A. Moncho-Jorda, F. Martinez-Lopez, M.A. Cabrerizo-Vilchez, R. Hidalgo Alvarez, M. Quesada-PMerez. 5: Kinetics of Particle and Protein Adsorption Z. Adamczyk.

Surface and Colloid Science

In the Johnson-Kendall-Roberts (JKR) approximation, adhesion forces outside the area of contact are neglected and elastic stresses at the edge of the contact are infinite, as in linear elastic fracture mechanics. On the other hand, in the Derjaguin-Muller-Toporov (DMT) approximation, the adhesion forces are taken into account, but the profile is assumed to be Hertzian, as if adhesion forces Could not deform the surfaces. To avoid self consistent numerical calculations based on a specific interaction model (Lennard-Jones potential for example) we have used a Dugdale model, which allows analytical solutions. The adhesion forces are assumed to have a constant value σO, the theoretical stress, over a length d at the crack tip. This internal loading acting in the air gap (the external crack) leads to a stress intensity factor Km, which is cancelled with the stress intensity factor KI due to the external loading. This cancellation suppresses the stress singularities, ensures the continuity of stresses, and fixes the radius c and the crack opening displacement δt. The energy release rate G is computed by the J-integral and the equilibrium is given by G = w. The equilibrium curves a(P), a(δ), and P(σ), the adherence forces at fixed load or fixed grips, the profiles, and the stress distributions can therefore be drawn as a function of a single parameter λ. When λ increases from zero to infinity there is a continuous transition from the DMT approximation to the JKR approximation. Furthermore the value of G for the DMT approximation is derived. It is shown that it is not physically consistent to have tensile stresses in the area of contact and no adhesion forces outside or no tensile stresses in the area of contact and adhesion forces outside. In the JKR approximation the distribution of adhesion forces is reduced to a singular stress at r = a+. The total attraction force outside the contact being zero, the integral of stresses in the contact is equal to the applied load P and negative applied loads are supported by the elastic restoring forces. In the DMT approximation the adhesion stresses tend toward zero to have a continuity with the stress at r = a−, but their integral is finite and the total attraction force outside the contact is 2πwR. In the area of contact the distribution of stresses is Hertzian, and their integral is P + 27πwR. Negative applied loads are sustained by adhesion forces outside the contact.

Adhesion of spheres : the JKR-DMT transition using a dugdale model

A review of experimental work on freezing and melting in confinement is presented. A range of systems, from metal oxide gels to porous glasses to novel nanoporous materials, is discussed. Features such as melting-point depression, hysteresis between freezing and melting, modifications to bulk solid structure and solid-solid transitions are reviewed for substances such as helium, organic fluids, water and metals. Recent work with well characterized assemblies of cylindrical pores like MCM-41 and graphitic microfibres with slit pores has suggested that the macroscopic picture of melting and freezing breaks down in pores of molecular dimensions. Applications of the surface force apparatus to the study of freezing and melting phenomena in confinement are discussed in some detail. This instrument is unique in allowing the study of conditions in a single pore, without the complications of pore blockage and connectivity effects. The results have confirmed the classical picture of melting-point depression in larger pores, and allowed the direct observation of capillary condensation of solid from vapour. Other results include the measurement of solvation forces across apparently fluid films below the bulk melting point and a solid-like response to shear of films above the bulk melting point. These somewhat contradictory findings highlight the difficulty of using bulk concepts to define the phase state of a substance confined to nanoscale pores.

https://iopscience.iop.org/article/10.1088/0953-8984/13/11/201/pdf

Confinement effects on freezing and melting

The interaction in water of neutral hydrocarbon and fluorocarbon surfaces, prepared by Langmuir-Blodgett deposition of surfactant monolayers, has been investigated. The attraction between these hydrophobic surfaces can be measured at separations of 70 to 90 nanometers and thus is of considerably greater range than previously found. Spontaneous cavitation occurred as soon as the fluorocarbon surfaces were brought into contact but occurred between the hydrocarbon surfaces only after separation from contact. The very long range forces measured are a consequence of the metastability of water films between macroscopic hydrophobic surfaces. Thus the hydrophobic interaction between macroscopic surfaces may not be related to water structure in the same way that the hydrophobic effect between nonpolar molecules is related to water structure.

https://science.sciencemag.org/content/sci/239/4838/390.full.pdf

Cavitation and the Interaction Between Macroscopic Hydrophobic Surfaces

Direct Measurements of the Force between Hydrophobic Surfaces in Water

A new method has been used to carry out accurate measurements of the hydrophobic interaction between uncharged hydrocarbon and fluorocarbon monolayer-coated surfaces in a surface force apparatus. The measurable range of the attraction between these deposited monolayers extends to a separation of 80 nm in conductivity water and can be approximated by an exponential function with two decay lengths of 2-3 and 13-16 nm, respectively. There is only a slight difference in the strength of the interaction between the fluorocarbon and hydrocarbon surfaces, in contrast to the significant difference in hydrophobicity as measured by the advancing contact angle of water. The authors suggest that the much shorter range attractive forces measured between monolayer adsorbed from solution are due to the formation of partial bilayers. They speculate that the very long range hydrophobic interaction found here is related to the metastability of water films between very hydrophobic surfaces.

Very long range attractive forces between uncharged hydrocarbon and fluorocarbon surfaces in water

Measurements have been made of the solvation forces between mica surfaces in the even‐numbered n‐alkanes from hexane to hexadecane. In all cases the force law is qualitatively very similar, characterized by a decaying oscillatory function of distance, as occurs for simple isotropic liquids. The spacing between successive minima in the force does not increase with carbon number, and is comparable to the width of a linear alkane molecule rather than its length or any average diameter. This suggests that the alkanes have some tendency towards a parallel orientation near the mica surfaces. The measurements give no indication of any strong repulsive component expected from mean‐field theories of higher alkanes or polymers. The results of one such theory are presented, and the reasons for its failure to match the experimental data are discussed.

https://dro.deakin.edu.au/eserv/DU:30041429/horn-structuringinliquid-1987.pdf

Hugo K. Christenson

Papers

Confinement effects on freezing and melting

Cavitation and the Interaction Between Macroscopic Hydrophobic Surfaces

Direct Measurements of the Force between Hydrophobic Surfaces in Water

Very long range attractive forces between uncharged hydrocarbon and fluorocarbon surfaces in water

Structuring in liquid alkanes between solid surfaces: Force measurements and mean‐field theory