Huimei An

TL;DR: The results suggested that oxidative stress may play an important role in antipsychotic-induced weight gain and further investigations using the longitudinal design in first-episode schizophrenia patients are needed to explore the beneficial effect of antioxidants on the abnormal lipid metabolism mediated by antipsychotics.

TL;DR: Examination of glucose and lipid metabolism in first-episode and drug naïve patients with schizophrenia and their relationships with psychopathology suggest abnormal glucose metabolism may be associated with the pathogenesis and psychopathology of schizophrenia in the early phases of the disease process.

TL;DR: In this paper, the authors performed 16S rRNA sequencing of stool samples from 36 patients with major depressive disorder and 45 healthy controls (HC) and found that six microbiota targets were associated with the severity of depression, 11 with sleep quality, and 3 with sleep severity.

TL;DR: Elevated levels of NMDar antibody may play a role in the pathogenesis of schizophrenia, leading to NMDAR dysfunction, thereby inducing symptoms of psychosis and cognitive impairment, and may serve as a biomarker and provide a new avenue for treatment of schizophrenia.

TL;DR: The results suggested that oxidative stress may be involved in the pathophysiology of schizophrenia at the early of stage and its cognitive impairment.