H
Hyeonjeong Jeong
Researcher at Daegu Gyeongbuk Institute of Science and Technology
Publications - 2
Citations - 107
Hyeonjeong Jeong is an academic researcher from Daegu Gyeongbuk Institute of Science and Technology. The author has contributed to research in topics: GSK3B & Phosphorylation. The author has an hindex of 2, co-authored 2 publications receiving 45 citations.
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Autophagic death of neural stem cells mediates chronic stress-induced decline of adult hippocampal neurogenesis and cognitive deficits.
Seonghee Jung,Seongwon Choe,Hanwoong Woo,Hyeonjeong Jeong,Hyun Kyu An,Hyewon Moon,Hye Young Ryu,Bo Kyoung Yeo,Ye Won Lee,Hyosun Choi,Ji Young Mun,Woong Sun,Han Kyoung Choe,Eun Kyoung Kim,Seong-Woon Yu +14 more
TL;DR: It is shown that chronic restraint stress suppresses adult hippocampal neurogenesis in mice by inducing autophagic cell death (ACD) of hippocampal neural stem cells (NSCs) through SGK3 (serum/glucocorticoid regulated kinase 3) without signs of apoptosis.
Journal ArticleDOI
GSK3B induces autophagy by phosphorylating ULK1
Hye Young Ryu,Leah Eunjung Kim,Hyeonjeong Jeong,Bo Kyoung Yeo,Ji-Won Lee,Hyeri Nam,Shinwon Ha,Hyun-Kyu An,Hyunhee Park,Seonghee Jung,Kyung Min Chung,Jiyea Kim,Byung-Hoon Lee,Heesun Cheong,Eun Kyoung Kim,Seong-Woon Yu +15 more
TL;DR: Following insulin withdrawal, GSK3B directly interacted with and activated ULK1 via phosphorylation of S405 and S415 within the GABARAP-interacting region, revealing the importance of G SK3B-mediated phosphorylated for ULK 1 regulation and autophagy induction and potentially for tumorigenesis.