H
Hyun-Kyoung Kim
Researcher at Chonbuk National University
Publications - 15
Citations - 226
Hyun-Kyoung Kim is an academic researcher from Chonbuk National University. The author has contributed to research in topics: Cancer & Unfolded protein response. The author has an hindex of 7, co-authored 15 publications receiving 132 citations. Previous affiliations of Hyun-Kyoung Kim include Korea Research Institute of Standards and Science.
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Journal ArticleDOI
TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium
Hyun-Kyoung Kim,Geum-Hwa Lee,Kashi Raj Bhattarai,Myung-Shik Lee,Sung Hoon Back,Hyung-Ryong Kim,Han-Jung Chae +6 more
TL;DR: TMBIM6, an ER membrane protein, is suggested to be a lysosomal Ca2+ modulator that coordinates with autophagy to alleviate metabolism stress.
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TMBIM6/BI-1 contributes to cancer progression through assembly with mTORC2 and AKT activation
Hyun-Kyoung Kim,Kashi Raj Bhattarai,Raghu Patil Junjappa,Jin Hee Ahn,Suvarna H. Pagire,Hyun Ju Yoo,Jaeseok Han,Duckgue Lee,Kyung-Woon Kim,Hyung-Ryong Kim,Han-Jung Chae +10 more
TL;DR: It is shown that TMBIM6 regulates AKT activation through mTORC2 assembly and ribosome association and an antagonist of TMBIm6 with anti-tumor properties is identified.
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Chromatin CKAP2, a new proliferation marker, as independent prognostic indicator in breast cancer.
Hanseong Kim,Jae-Soo Koh,Yong-Bock Choi,Jungsil Ro,Hyun-Kyoung Kim,Mi-Kyung Kim,Byung-Ho Nam,Kyung-Tae Kim,Vishal Chandra,Hyesil Seol,Woo-Chul Noh,Eun Kyu Kim,Joobae Park,Chang-Dae Bae,Kyeong-Man Hong +14 more
TL;DR: Ch Chromatin CKAP2 is an independent prognostic marker for RFS in early-stage breast cancer, and could potentially replace the MAI in clinical evaluation of proliferation activity, according to the results of this study.
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Magnetic properties and texture of NdFeB magnets fabricated by current-applied-pressure-assisted process
TL;DR: In this article, the current-applied-pressure-assisted (CAPA) process has been applied to obtain full dense isotropic and anisotropic NdFeB magnets from melt spun MQP-A alloy.
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The correlation of IRE1α oxidation with Nox4 activation in aging-associated vascular dysfunction.
TL;DR: The state of Nox4-based ER redox imbalance/ROS accumulation is suggested to determine the pathway “the UPR; IRE1α phosphorylation and XBP-1 splicing and the UPR failure; I RE1α cysteine-based oxidation, especially sulfonation, finally controlling aging-associated vascular dysfunction.