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Hyun-Woo Kim

Researcher at Seoul National University

Publications -  431
Citations -  5448

Hyun-Woo Kim is an academic researcher from Seoul National University. The author has contributed to research in topics: Medicine & Engineering. The author has an hindex of 33, co-authored 369 publications receiving 4615 citations. Previous affiliations of Hyun-Woo Kim include Baewha Women's University & Chungnam National University.

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Toxicity and tissue distribution of magnetic nanoparticles in mice

Jun Sung Kim, +9 more
- 01 Jan 2006 - 
TL;DR: Magnetic nanoparticles of 50-nm size did not cause apparent toxicity under the experimental conditions of this study, indicating that such nanosized materials can penetrate blood-brain barrier without disturbing its function or producing apparent toxicity.
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Comparison of doxazosin with or without tolterodine in men with symptomatic bladder outlet obstruction and an overactive bladder.

Ji Youl Lee, +5 more
- 01 Oct 2004 - 
TL;DR: In a study of patients with BOO and an overactive bladder, authors compared the use of doxazosin with or without tolterodine to find the combination of the two drugs was helpful in most patients, but the combination alone was also effective.
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Mannosylated chitosan nanoparticle–based cytokine gene therapy suppressed cancer growth in BALB/c mice bearing CT-26 carcinoma cells

Tae Hee Kim, +4 more
- 01 Jul 2006 - 
TL;DR: Mannosylated chitosan (MC) was prepared to induce mannose receptor–mediated endocytosis of IL-12 gene directly into dendritic cells which reside within the tumor, and was proven to be suitable for IL- 12 gene delivery due to good physicochemical properties and low cytotoxicity.
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Intrathecal injection of the ς1 receptor antagonist BD1047 blocks both mechanical allodynia and increases in spinal NR1 expression during the induction phase of rodent neuropathic pain

Dae Hyun Roh, +9 more
- 01 Nov 2008 - 
TL;DR: Results demonstrate that spinal Sig-1Rs play a critical role in both the induction of mechanical allodynia and the activation of spinal N-methyl-d-aspartate receptors in CCI rats and suggest a potential therapeutic role for the use of Sig- 1R antagonists in the clinical management of neuropathic pain.
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Activation of the spinal sigma‐1 receptor enhances NMDA‐induced pain via PKC‐ and PKA‐dependent phosphorylation of the NR1 subunit in mice

Hyun-Woo Kim, +8 more
- 01 Jul 2008 - 
TL;DR: It is demonstrated that the spinal sigma‐1 receptor (Sig‐1 R) plays an important role in pain transmission, although the exact mechanism is still unclear and there are no studies addressing whether Sig-1 R activation directly affects NMDA receptor sensitivity.