I
I M Tomlinson
Publications - 1
Citations - 1286
I M Tomlinson is an academic researcher. The author has contributed to research in topics: Phage display & Synthetic antibody. The author has an hindex of 1, co-authored 1 publications receiving 1277 citations.
Papers
More filters
Journal ArticleDOI
Isolation of high affinity human antibodies directly from large synthetic repertoires.
Andrew D. Griffiths,S C Williams,Oliver Hartley,I M Tomlinson,Peter M. Waterhouse,William L. Crosby,Roland E. Kontermann,Peter T. Jones,N. M. Low,T. J. Allison +9 more
TL;DR: This work created highly diverse repertoires of heavy and light chains entirely in vitro from a bank of human V gene segments and generated a large synthetic repertoire of Fab fragments displayed on filamentous phage to help dissect the contributions of biological mechanisms and structural features governing V gene usage in vivo.