Author
Iain H Wilson
Bio: Iain H Wilson is an academic researcher from National Health Service. The author has contributed to research in topics: Global health. The author has an hindex of 3, co-authored 3 publications receiving 1635 citations.
Topics: Global health
Papers
More filters
Harvard University1, Boston Children's Hospital2, King's College London3, Lund University4, Massachusetts Eye and Ear Infirmary5, University of São Paulo6, University of California, San Diego7, Imperial College London8, Brigham and Women's Hospital9, Partners In Health10, Royal North Shore Hospital11, Medical College of Wisconsin12, Nanyang Technological University13, Monash University14, University of Sierra Leone15, University of Oxford16, Mongolian National University17, Flinders University18, University of Malawi19, Beth Israel Deaconess Medical Center20, Bhabha Atomic Research Centre21, Royal Australasian College of Surgeons22, Stanford University23, University of California, San Francisco24
TL;DR: The need for surgical services in low- and middleincome countries will continue to rise substantially from now until 2030, with a large projected increase in the incidence of cancer, road traffic injuries, and cardiovascular and metabolic diseases in LMICs.
2,209 citations
Harvard University1, Boston Children's Hospital2, King's College London3, Lund University4, Massachusetts Eye and Ear Infirmary5, University of São Paulo6, University of California, San Diego7, Imperial College London8, Brigham and Women's Hospital9, Royal North Shore Hospital10, Medical College of Wisconsin11, Nanyang Technological University12, University of Sierra Leone13, University of Oxford14, Mongolian National University15, University of Malawi16, Beth Israel Deaconess Medical Center17, Bhabha Atomic Research Centre18, Royal Australasian College of Surgeons19, Stanford University20, University of California, San Francisco21
TL;DR: The Lancet Commission on Global Surgery has five key messages, a set of indicators and recommendations to improve access to safe, affordable surgical and anaesthesia care in LMICs, and a template for a national surgical plan.
185 citations
Boston Children's Hospital1, King's College London2, Lund University3, Massachusetts Eye and Ear Infirmary4, University of São Paulo5, University of California, San Diego6, Imperial College London7, Brigham and Women's Hospital8, Royal North Shore Hospital9, Medical College of Wisconsin10, Nanyang Technological University11, University of Sierra Leone12, University of Oxford13, Mongolian National University14, University of Malawi15, Beth Israel Deaconess Medical Center16, Harvard University17, Bhabha Atomic Research Centre18, Royal Australasian College of Surgeons19, Stanford University20, National Health Service21, University of California, San Francisco22
TL;DR: John G Meara*, Andrew J M Leather*, Lars Hagander*, Blake C Alkire, Nivaldo Alonso, Emmanuel A Ameh, Stephen W Bickler, Lesong Conteh, Anna J Dare, Justine Davies, Eunice Dérivois Mérisier, Shenaaz El-Halabi, Paul E Farmer, Atul Gawande, Rowan Gillies, Sarah L M Greenberg, Caris E Grimes, Russell L Gruen,
16 citations
Cited by
More filters
TL;DR: For most cancers, 5-year net survival remains among the highest in the world in the USA and Canada, in Australia and New Zealand, and in Finland, Iceland, Norway, and Sweden, while for many cancers, Denmark is closing the survival gap with the other Nordic countries.
2,756 citations
Harvard University1, New York University2, World Bank3, Mexican Social Security Institute4, Wellcome Trust5, Inter-American Development Bank6, University of Ibadan7, Northwestern University8, Bill & Melinda Gates Foundation9, Malawi University of Science and Technology10, University of London11, Duke University12, University of Bergen13, Public Health Foundation of India14, Centers for Disease Control and Prevention15, Stanford University16, Kathmandu17
TL;DR: High-quality health systems in the Sustainable Development Goals era: time for a revolution.
1,434 citations
TL;DR: The InTBIR Participants and Investigators have provided informed consent for the study to take place in Poland.
Abstract: Additional co-authors: Endre Czeiter, Marek Czosnyka, Ramon Diaz-Arrastia, Jens P Dreier, Ann-Christine Duhaime, Ari Ercole, Thomas A van Essen, Valery L Feigin, Guoyi Gao, Joseph Giacino, Laura E Gonzalez-Lara, Russell L Gruen, Deepak Gupta, Jed A Hartings, Sean Hill, Ji-yao Jiang, Naomi Ketharanathan, Erwin J O Kompanje, Linda Lanyon, Steven Laureys, Fiona Lecky, Harvey Levin, Hester F Lingsma, Marc Maegele, Marek Majdan, Geoffrey Manley, Jill Marsteller, Luciana Mascia, Charles McFadyen, Stefania Mondello, Virginia Newcombe, Aarno Palotie, Paul M Parizel, Wilco Peul, James Piercy, Suzanne Polinder, Louis Puybasset, Todd E Rasmussen, Rolf Rossaint, Peter Smielewski, Jeannette Soderberg, Simon J Stanworth, Murray B Stein, Nicole von Steinbuchel, William Stewart, Ewout W Steyerberg, Nino Stocchetti, Anneliese Synnot, Braden Te Ao, Olli Tenovuo, Alice Theadom, Dick Tibboel, Walter Videtta, Kevin K W Wang, W Huw Williams, Kristine Yaffe for the InTBIR Participants and Investigators
1,354 citations
TL;DR: The aim of this study was to provide evidence that palliative care and pain relief research should be considered as a continuum of treatment for patients with life-threatening illnesses.
683 citations
TL;DR: Several new opioids have been developed that modulate μ-receptor activity by selectively engaging intracellular pathways associated with analgesia and not those associated with adverse events, creating a wider therapeutic window than unselective conventional opioids.
Abstract: This review provides an overview of the clinical issue of poorly controlled postoperative pain and therapeutic approaches that may help to address this common unresolved health-care challenge. Postoperative pain is not adequately managed in greater than 80% of patients in the US, although rates vary depending on such factors as type of surgery performed, analgesic/anesthetic intervention used, and time elapsed after surgery. Poorly controlled acute postoperative pain is associated with increased morbidity, functional and quality-of-life impairment, delayed recovery time, prolonged duration of opioid use, and higher health-care costs. In addition, the presence and intensity of acute pain during or after surgery is predictive of the development of chronic pain. More effective analgesic/anesthetic measures in the perioperative period are needed to prevent the progression to persistent pain. Although clinical findings are inconsistent, some studies of local anesthetics and nonopioid analgesics have suggested potential benefits as preventive interventions. Conventional opioids remain the standard of care for the management of acute postoperative pain; however, the risk of opioid-related adverse events can limit optimal dosing for analgesia, leading to poorly controlled acute postoperative pain. Several new opioids have been developed that modulate μ-receptor activity by selectively engaging intracellular pathways associated with analgesia and not those associated with adverse events, creating a wider therapeutic window than unselective conventional opioids. In clinical studies, oliceridine (TRV130), a novel μ-receptor G-protein pathway-selective modulator, produced rapid postoperative analgesia with reduced prevalence of adverse events versus morphine.
678 citations