Ian Sillitoe

TL;DR: Recent developments with InterPro are reported, including the addition of two new databases, and the functionality to include residue-level annotation and prediction of intrinsic disorder, which enrich the annotations provided by InterPro, increase the overall number of residues annotated and allow more specific functional inferences.

TL;DR: The new domain architecture search tool is described and the process of mapping of Gene Ontology terms to InterPro is outlined, and the challenges faced by the resource given the explosive growth in sequence data in recent years are discussed.

TL;DR: Recent developments with InterPro (version 70.0) and its associated software are reported, including an 18% growth in the size of the database in terms on new InterPro entries, updates to content, the inclusion of an additional entry type, refined modelling of discontinuous domains, and the development of a new programmatic interface and website.

TL;DR: The status of InterPro (version 81.0) in its 20th year of operation, and its associated software, is reported, including updates to database content, the release of a new website and REST API, and performance improvements in InterProScan.

TL;DR: This article provides an update on the major developments in the 2 years since the last publication in this journal including: significant improvements to the predictive power of the authors' functional families (FunFams); the release of their ‘current’ putative domain assignments (CATH-B); a new, strictly non-redundant data set of CATH domains suitable for homology benchmarking experiments (Cath-40) and a number of improved to the web pages.