Igor J. Pesun

Bio: Igor J. Pesun is an academic researcher from University of Manitoba. The author has contributed to research in topics: Denture Liners & Implant. The author has an hindex of 15, co-authored 37 publications receiving 1649 citations. Previous affiliations of Igor J. Pesun include University of Minnesota.

Current ceramic materials and systems with clinical recommendations: A systematic review

Abstract: Statement of problem Developments in ceramic core materials such as lithium disilicate, aluminum oxide, and zirconium oxide have allowed more widespread application of all-ceramic restorations over the past 10 years. With a plethora of ceramic materials and systems currently available for use, an overview of the scientific literature on the efficacy of this treatment therapy is indicated. Purpose This article reviews the current literature covering all-ceramic materials and systems, with respect to survival, material properties, marginal and internal fit, cementation and bonding, and color and esthetics, and provides clinical recommendations for their use. Material and methods A comprehensive review of the literature was completed seeking evidence for the treatment of teeth with all-ceramic restorations. A search of English language peer-reviewed literature was undertaken using MEDLINE and PubMed with a focus on evidence-based research articles published between 1996 and 2006. A hand search of relevant dental journals was also completed. Randomized controlled trials, nonrandomized controlled studies, longitudinal experimental clinical studies, longitudinal prospective studies, and longitudinal retrospective studies were reviewed. The last search was conducted on June 12, 2007. Data supporting the clinical application of all-ceramic materials and systems was sought. Results The literature demonstrates that multiple all-ceramic materials and systems are currently available for clinical use, and there is not a single universal material or system for all clinical situations. The successful application is dependent upon the clinician to match the materials, manufacturing techniques, and cementation or bonding procedures, with the individual clinical situation. Conclusions Within the scope of this systematic review, there is no evidence to support the universal application of a single ceramic material and system for all clinical situations. Additional longitudinal clinical studies are required to advance the development of ceramic materials and systems.

Accuracy of two impression techniques with angulated implants

Abstract: Statement of problem Accurate recording of implant locations is required so that definitive restorations are properly supported and do not place additional stress on the implants. Angulated implants may result in inaccurate impressions, and the impression technique may affect the accuracy of the definitive cast. Purpose The purpose of this study was to determine the effect the combined interaction of impression technique, implant angulation, and implant number has on the accuracy of implant definitive casts. Material and methods One definitive stone cast was fabricated for each of 6 experimental groups and 1 control group. All 7 definitive casts had 3 implants arranged in a triangular pattern creating a plane. In the 6 experimental groups, the center implant was perpendicular to the plane of the cast while the outer implants had 5, 10, or 15 degrees convergence towards or divergence away from the center implant. The control definitive cast had all 3 implants parallel to each another and perpendicular to the plane of the cast. Five open tray and 5 closed tray addition silicone impressions were made of each definitive cast. Impressions were poured with type IV dental stone, and a fine tip measuring stylus was used to record multiple axis (X-Y-Z) coordinates on the top surface of the implant hex and on the cast base. Computer software was used to align the data sets and vector calculations determined the difference in degrees between the implant angles in the definitive cast and the duplicate casts. Statistical analysis used repeated-measures ANOVA (α=.05) with post-hoc tests of significant interactions. Results The angle errors for the closed and open tray impression techniques did not differ significantly ( P =.22). Implant angulations and implant numbers differed in average angle errors but not in any easily interpreted pattern ( P P =.19). Conclusions The average angle errors for the closed and open tray impression techniques did not differ significantly. There was no interpretable pattern of average angle errors in terms of implant angulation and implant number. The magnitude of distortion was similar for all combinations of impression technique, implant angulation, and implant number.

A preliminary survey of interprofessional education.

Abstract: The purpose of this article is to review the literature on interprofessional education (IPE) and report on a preliminary survey of the current status of interprofessional education in seven academic health centers (AHCs) that have schools of dentistry associated with them. There is wide variability in interpretation of the term "interprofessional," and many barriers to interprofessional education exist including already overcrowded curricula in health professions schools, lack of support from faculty and administration, and financial constraints. Based on interviews completed at the authors' home institutions, it was recommended that topics such as ethics, communication skills, evidence-based practice, and informatics could be effectively taught in an interprofessional manner. Currently, some academic health centers are attempting to develop interprofessional education programs, but most of these efforts do not include dental students. Of the seven AHCs investigated in this study, only two had formal interprofessional educational activities that involved students from two or more health professions education programs. Dental school participants in this study professed a strong interest in interprofessional programs, but many interviewees from other professional schools and AHC administrators perceived that the dental school was isolated from other schools and disinterested in IPE. Many health care setting models in the future will include dentists as part of an interdisciplinary health care team; consequently, it is important for dental schools to become an active participant in future interprofessional educational initiatives.

Systematic review of the survival rate and the incidence of biological, technical, and aesthetic complications of single crowns on implants reported in longitudinal studies with a mean follow-up of 5 years

Abstract: Objective To assess the 5-year survival of implant-supported single crowns (SCs) and to describe the incidence of biological, technical, and aesthetic complications. The focused question was: What is the survival rate of implants supporting single crowns and implant-supported crowns with a mean follow-up of 5 years and to which extent do biological, technical, and aesthetic complications occur? Methods A Medline search (2006–2011) was performed for clinical studies focusing on implant-supported SCs with a mean follow-up of at least 5 years. The search was complemented by an additional hand search and the inclusion of 24 studies from a previous systematic review (Jung et al. 2008a). Survival and complication rates were analyzed using random-effects Poisson's regression models to obtain summary estimates of 5- and 10-year proportions. Results Forty-six studies derived from an initial search count of 1083 titles and the complementary publications from the previous systematic review (Jung et al. 2008a) were selected and the data were extracted. Based on the meta-analysis, survival of implants supporting SCs at 5 years amounted to 97.2% (95% CI: 96.3–97.9%), and at 10 years amounted to 95.2% (95% CI: 91.8–97.2%). The survival of implant-supported SCs was 96.3% (95% CI: 94.2–97.6%) after 5 years and 89.4% (95% CI: 82.8–93.6%) after 10 years. For biological complications, a 5-year cumulative soft tissue complication rate of 7.1% (95% CI: 4.4–11.3%) and a cumulative complication rate for implants with bone loss >2 mm of 5.2% (95% CI: 3.1–8.6%) were calculated. Technical complications reached a cumulative incidence of 8.8% (95% CI: 5.1–15.0%) for screw-loosening, 4.1% (95% CI: 2.2–7.5%) for loss of retention, and 3.5% (95% CI: 2.4–5.2%) for fracture of the veneering material after 5 years. The cumulative 5-year aesthetic complication rate amounted to 7.1% (95% CI: 3.6–13.6%). Conclusions The outcomes of the meta-analysis demonstrated high implant survival rates for both the single tooth implants and the respective single crowns after 5 and 10 years. However, technical, biological, and aesthetic complications were frequent.

A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health.

Abstract: Ng Y-L, Mann V, Gulabivala K. A prospective study of the factors affecting outcomes of nonsurgical root canal treatment: part 1: periapical health. International Endodontic Journal. Aim To investigate the probability of and factors influencing periapical status of teeth following primary (1! RCTx) or secondary (2! RCTx) root canal treatment. Methodology This prospective study involved annual clinical and radiographic follow-up of 1! RCTx (1170 roots, 702 teeth and 534 patients) or 2! RCTx (1314 roots, 750 teeth and 559 patients) carried out by Endodontic postgraduate students for 2‐4 (50%) years. Pre-, intra- and postoperative data were collected prospectively on customized forms. The proportion of roots with complete periapical healing was estimated, and prognostic factors were investigated using multiple logistic regression models. Clustering effects within patients were adjusted in all models using robust standard error. Results The proportion of roots with complete periapical healing after 1! RCTx (83%; 95% CI: 81%, 85%) or 2! RCTx (80%; 95% CI: 78%, 82%) were similar. Eleven prognostic factors were identified. The conditions that were found to improve periapical healing significantly were: the preoperative absence of a periapical lesion (P = 0.003); in presence of a periapical lesion, the smaller its size (P £ 0.001), the better the treatment prognosis; the absence of a preoperative sinus tract (P = 0.001); achievement of patency at the canal terminus (P = 0.001); extension of canal cleaning as close as possible to its apical terminus (P = 0.001); the use of ethylene-diaminetetra-acetic acid (EDTA) solution as a penultimate wash followed by final rinse with NaOCl solution in 2! RCTx cases (P = 0.002); abstaining from using 2% chlorexidine as an adjunct irrigant to NaOCl solution (P = 0.01); absence of tooth/root perforation (P = 0.06); absence of interappointment flare-up (pain or swelling) (P = 0.002); absence of root-filling extrusion (P £ 0.001); and presence of a satisfactory coronal restoration (P £ 0.001). Conclusions Success based on periapical health associated with roots following 1! RCTx (83%) or 2! RCTx (80%) was similar, with 10 factors having a common effect on both, whilst the 11th factor ‘EDTA as an additional irrigant’ had different effects on the two treatments.

Advances in Biomaterials for Drug Delivery.

Abstract: Advances in biomaterials for drug delivery are enabling significant progress in biology and medicine. Multidisciplinary collaborations between physical scientists, engineers, biologists, and clinicians generate innovative strategies and materials to treat a range of diseases. Specifically, recent advances include major breakthroughs in materials for cancer immunotherapy, autoimmune diseases, and genome editing. Here, strategies for the design and implementation of biomaterials for drug delivery are reviewed. A brief history of the biomaterials field is first established, and then commentary on RNA delivery, responsive materials development, and immunomodulation are provided. Current challenges associated with these areas as well as opportunities to address long-standing problems in biology and medicine are discussed throughout.

Accuracy of complete-arch dental impressions: a new method of measuring trueness and precision.

Abstract: STATEMENT OF PROBLEM: A new approach to both 3-dimensional (3D) trueness and precision is necessary to assess the accuracy of intraoral digital impressions and compare them to conventionally acquired impressions. PURPOSE: The purpose of this in vitro study was to evaluate whether a new reference scanner is capable of measuring conventional and digital intraoral complete-arch impressions for 3D accuracy. MATERIAL AND METHODS: A steel reference dentate model was fabricated and measured with a reference scanner (digital reference model). Conventional impressions were made from the reference model, poured with Type IV dental stone, scanned with the reference scanner, and exported as digital models. Additionally, digital impressions of the reference model were made and the digital models were exported. Precision was measured by superimposing the digital models within each group. Superimposing the digital models on the digital reference model assessed the trueness of each impression method. Statistical significance was assessed with an independent sample t test (α=.05). RESULTS: The reference scanner delivered high accuracy over the entire dental arch with a precision of 1.6 ±0.6 µm and a trueness of 5.3 ±1.1 µm. Conventional impressions showed significantly higher precision (12.5 ±2.5 µm) and trueness values (20.4 ±2.2 µm) with small deviations in the second molar region (P<.001). Digital impressions were significantly less accurate with a precision of 32.4 ±9.6 µm and a trueness of 58.6 ±15.8µm (P<.001). More systematic deviations of the digital models were visible across the entire dental arch. CONCLUSIONS: The new reference scanner is capable of measuring the precision and trueness of both digital and conventional complete-arch impressions. The digital impression is less accurate and shows a different pattern of deviation than the conventional impression.