Indranil Basu

Bio: Indranil Basu is an academic researcher from Indian Institute of Technology Madras. The author has contributed to research in topics: Potentiometric sensor & Silicon. The author has an hindex of 2, co-authored 3 publications receiving 84 citations.

Solid state potentiometric sensor for the estimation of tributyrin and urea

Abstract: We report fabrication of a potentiometric biosensor on silicon for the estimation of tributyrin and urea based on enzymatic reactions. The sensor is an electrolyte–insulator–semiconductor capacitor (EISCAP) that shows a shift in the measured C–V with changes in the pH of the electrolyte. This pH shift can be induced by the enzyme-mediated hydrolysis of tributyrin and urea which results in acidic and basic solutions, respectively and an EISCAP can be effectively used for the detection of these bioanalytes. A silicon nitride based EISCAP was used for the first time to detect triglycerides and urea. The sensor was able to detect millimolar concentrations of the bioanalytes (tributyrin/urea). The most important features of the tributyrin and urea sensor are high sensitivity, long life-time, easily built at a low cost, micro-construction and short response time. Optimization of the conditions for the enzymatic reaction and calibration of the sensor are included.

Potentiometric biosensors based on silicon and porous silicon

Abstract: We report fabrication of potentiometric biosensors with silicon for the estimation of triglycerides and urea based on enzymatic reactions. The sensor is an Electrolyte–InsulatorSemiconductor capacitor (EISCAP) that shows a shift in the measured CV with changes in the pH of the electrolyte. Enzyme mediated biological reactions involve changes in the pH of the electrolyte and an EISCAP can be effectively used for detection of biological compounds. Optimization of the conditions for the enzymatic reaction and calibration of the sensor are included. Effect of replacing silicon with porous silicon is discussed.

Porous silicon chemical sensors and biosensors: A review

Abstract: The use of porous silicon (PSi) as a sensor for detection of various analytes is reviewed. The optical or electrical properties of PSi are key sensing parameters that have been used in many chemical and biological sensing applications. PSi is a promising candidate due to ease of fabrication, large surface area, various accessible pore sizes and morphologies, controllable surface modification and its compatibility with conventional silicon processing technology. The adsorption of chemical or biological molecules into the pores modifies the electrical and/or optical properties, allowing convenient and sensitive measurement approach. In this review, we provide a critical assessment of the development of PSi as a promising material for chemical and biosensing applications. Formation procedures of PSi with various pore sizes and morphologies are firstly given. Surface properties and structural characteristics of the material are briefly described. The recent progress on utilization of such porous structures in chemical and biosensing applications is then addressed in the context of surface chemistry effects and nanostructures, measuring approaches, operating concepts and device sensitivity and stability. Finally, concluding remarks with existing challenges that hinder the material for commercial use are highlighted.

Bio FEDs (Field‐Effect Devices): State‐of‐the‐Art and New Directions

Abstract: This paper gives a brief survey on biologically sensitive FEDs (field-effect devices) and introduces some recent approaches in this field. Basic concepts, functional principles and current trends in research and development for namely, ISFETs (ion-sensitive field-effect transistors), capacitive EIS (electrolyte-insulator-semiconductor) sensors and LAPS (light-addressable potentiometric sensor) structures will be presented.

Common milk adulteration and their detection techniques

Abstract: Food adulteration is a global concern and developing countries are at higher risk associated with it due to lack of monitoring and policies. However, this is one of the most common phenomena that has been overlooked in many countries. Unfortunately, in contrast to common belief, milk adulterants can pose serious health hazards leading to fatal diseases. This paper presents a detailed review of common milk adulterants as well as different methods to detect the adulterants both qualitatively and quantitatively. This study is organized to be an 'adulterant based' study instead of 'techniques based' one, where qualitative detection for most of the common adulterants are enlisted and quantitative detection methods are limited to few major adulterants of milk. Apart from regular techniques, recent development in these detection techniques have also been reported. Nowadays milk is being adulterated in more sophisticated ways that demands for cutting edge research for the detection of the adulterants. This review intends to contribute towards the common knowledge base regarding possible milk adulterants and their detection techniques.