scispace - formally typeset
I

Irene Keller

Researcher at Swiss Institute of Bioinformatics

Publications -  74
Citations -  6002

Irene Keller is an academic researcher from Swiss Institute of Bioinformatics. The author has contributed to research in topics: Population & Genetic structure. The author has an hindex of 27, co-authored 69 publications receiving 5123 citations. Previous affiliations of Irene Keller include ETH Zurich & Swiss Ornithological Institute.

Papers
More filters
Journal ArticleDOI

The genomic substrate for adaptive radiation in African cichlid fish

David Brawand, +82 more
- 18 Sep 2014 - 
TL;DR: This article found an excess of gene duplications in the East African lineage compared to Nile tilapia and other teleosts, an abundance of non-coding element divergence, accelerated coding sequence evolution, expression divergence associated with transposable element insertions, and regulation by novel microRNAs.

The genomic substrate for adaptive radiation in African cichlid fish

David Brawand, +82 more
TL;DR: It is concluded that a number of molecular mechanisms shaped East African cichlid genomes, and that amassing of standing variation during periods of relaxed purifying selection may have been important in facilitating subsequent evolutionary diversification.
Journal ArticleDOI

Genome-wide RAD sequence data provide unprecedented resolution of species boundaries and relationships in the Lake Victoria cichlid adaptive radiation

TL;DR: This work uses NGS data generated from reduced representation genomic libraries of restriction‐site‐associated DNA (RAD) markers to infer phylogenetic relationships among 16 species of cichlid fishes from a single rocky island community within Lake Victoria's cICHlid adaptive radiation, and produces phylogenetic trees with unprecedented resolution for this group.
Journal ArticleDOI

The outer mucus layer hosts a distinct intestinal microbial niche

TL;DR: It is shown that the outer mucus of the large intestine forms a unique microbial niche with distinct communities, including bacteria without specialized mucolytic capability, and bacterial species present in the mucus show differential proliferation and resource utilization compared with the same species in the intestinal lumen.