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Irfan J. Lodhi

Researcher at Washington University in St. Louis

Publications -  50
Citations -  8448

Irfan J. Lodhi is an academic researcher from Washington University in St. Louis. The author has contributed to research in topics: Lipid metabolism & Peroxisome. The author has an hindex of 25, co-authored 43 publications receiving 7240 citations. Previous affiliations of Irfan J. Lodhi include Veterans Health Administration & University of Michigan.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Identification of a Physiologically Relevant Endogenous Ligand for PPARα in Liver

TL;DR: The FAS-dependent presence of a phospholipid bound to PPAR alpha isolated from mouse liver is demonstrated and data suggest that 16:0/18:1-GPC is a physiologically relevant endogenous PPARalpha ligand.
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Peroxisomes: a nexus for lipid metabolism and cellular signaling.

TL;DR: The biology of peroxisomes is reviewed and their potential relevance to human disorders including cancer, obesity-related diabetes, and degenerative neurologic disease is reviewed.
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Structural and functional roles of ether lipids

TL;DR: In addition to their structural roles, a subset of ether lipids are thought to function as endogenous antioxidants, and emerging studies suggest that they are involved in cell differentiation and signaling pathways.
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Inhibiting Adipose Tissue Lipogenesis Reprograms Thermogenesis and PPARγ Activation to Decrease Diet-Induced Obesity

TL;DR: It is demonstrated that an adipocyte lipogenic pathway encompassing fatty acid synthase and PexRAP modulates endogenous PPARγ activation and adiposity, and suggested that inhibiting PxRAP or related lipogenic enzymes could treat obesity and diabetes.