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Irwin J. Kopin

Researcher at National Institutes of Health

Publications -  627
Citations -  40872

Irwin J. Kopin is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Catecholamine & Norepinephrine (medication). The author has an hindex of 105, co-authored 627 publications receiving 40141 citations. Previous affiliations of Irwin J. Kopin include Slovak Academy of Sciences & Karolinska Institutet.

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Chronic Parkinsonism secondary to intravenous injection of meperidine analogues.

Glenn C. Davis, +6 more
- 01 Dec 1979 - 
TL;DR: Biogenic amines and metabolites in the cerebrospinal fluid and microscopic evaluation of the brain at necropsy were consistent with damage to aminergic neurons in the substantia nigra.
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Catecholamine Metabolism: A Contemporary View with Implications for Physiology and Medicine

Graeme Eisenhofer, +2 more
- 01 Sep 2004 - 
TL;DR: The large contribution of intraneuronal deamination to catecholamine turnover, and dependence of this on the vesicular-axoplasmic monoamine exchange process, helps explain how synthesis, release, metabolism, turnovers, and stores of catechlamines are regulated in a coordinated fashion during stress and in disease states.
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Use of plasma norepinephrine for evaluation of sympathetic neuronal function in man.

C R Lake, +2 more
- 01 Jun 1976 - 
TL;DR: Levels of norepinephrine in human plasma have been determined by a radioenzymatic technique sufficiently sensitive to measure 0.014 ng NE per ml plasma by evaluating sympathetic neuronal function based on the increments in plasma NE produced by postural change and a standard amount of exertion.
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Validity and reliability of liquid chromatography with electrochemical detection for measuring plasma levels of norepinephrine and epinephrine in man.

David S. Goldstein, +4 more
- 02 Feb 1981 - 
TL;DR: Liquid chromatography with electrochemical detection (LCEC) provides a rapid, sensitive, and specific technique for measuring human plasma norepinephrine and epinephrine levels against that of the catechol-O-methyl-transferase radioenzymatic (COMT-RE) assay.
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Simultaneous liquid-chromatographic determination of 3,4-dihydroxyphenylglycol, catecholamines, and 3,4-dihydroxyphenylalanine in plasma, and their responses to inhibition of monoamine oxidase.

Graeme Eisenhofer, +6 more
- 01 Nov 1986 - 
TL;DR: The reversed-phase liquid-chromatographic method is rapid, reliable, and simple, and it provides a more comprehensive assessment of noradrenergic nervous function than does measurement only of catecholamines.