Isabell Speer

TL;DR: This study presents novel formulations containing isoniazid for prevention of latent tuberculosis and investigates 3D printing technology for personalized production of oral solid dosage forms enabling adjustable dose and drug release properties.

TL;DR: Developing a thin film produced by solvent casting, which is rapidly disintegrating when placed in the mouth, but which provides prolonged drug release characteristics by incorporating drug‐loaded matrix particles (MPs) is developed.

TL;DR: The suitability to investigate varying types of ODFs applying the four different test methods highly depends on the intended purpose, and the slide frame and SFaB method seems to be particularly applicable for research and development purposes, whereas the PharmaTest® disintegration tester and the SF aB method fulfil the demands required for testing methods within the quality control.

TL;DR: The production of rapidly disintegrating ODFs with prolonged release properties for DS, representing a freely water‐soluble drug, was feasible and feasible and produced MPs with a drug load of 70% and diclofenac sodium as model drug.

TL;DR: Due to the simple and well standardized instrumental setup as well as high robustness, the basket and PGD method are particularly suitable for use in pharmaceutical quality control, and may be used to simulate gastrointestinal transit.