https://serval.unil.ch/resource/serval:BIB_BF6AD527CFAB.P001/REF.pdf

The application of different 3D-scan-systems and photogrammetry at an excavation — A Neolithic dolmen from Switzerland

The availability of 3D scanning devices allows performing the process of digitisation of a growing number of diverse museum artefacts. After the properly conducted processing of the acquired point cloud, the authors obtained a photorealistic digital copy that can be presented in many ways. With regard to the objects from archaeological excavations, the vast majority are the artefacts that are more or less damaged or only partially preserved. Their state of preservation, specialised archaeological knowledge and the use of appropriate 3D computer technologies allow their complete digital reconstruction. The present work concerns the development of alternative methods and algorithms of conduct, the selection of programs and tools to recreate the surface of the outer and inner side and the bottom of a 12th century pitcher from the Afrasiab excavations in Uzbekistan.

/pdf/photorealistic-3d-digital-reconstruction-of-a-clay-pitcher-opbvmptw5q.pdf

Photorealistic 3D Digital Reconstruction of a Clay Pitcher

An integrated 3D shape analysis and scientific visualization approach to the study of a Late Bronze Age unique stone object from Pyla-Kokkinokremos, Cyprus

Finding Archaeology in 2017: What Is Archaeology and Why Are We Doing It? Why Should We Be Doing It?

Lymphocytes mount protective immunity from infectious pathogens and from cancer. Their engagement by target antigens prompt activation, differentiation to effector cells and proliferation. These responses require energy that is generated by cellular metabolic processes, such as glycolysis and oxidative phosphorylation. Glycolysis occurs in the cytoplasm while oxidative phosphorylation occurs in the mitochondria. Energy in the form of adenosine triphosphate is generated from the uptake of glucose, amino acids and free fatty acids. Important recent evidence indicates that naive and activated lymphocytes and functionally distinct subsets preferentially use different metabolic pathways for their energy needs. Thus, effector Th17 cells primarily use glycolysis to generate energy required for their activities. Memory T and B cells and regulatory T cells, in contrast, rely on mitochondrial metabolism for their energy requirements. Naive T and B are in a quiescent state with small mitochondria. Extrinsic factors such as oxygen tension and intrinsic substrates can also influence the choice of metabolic pathways and functional flexibility. Studies of lymphocytes in disease states reveal alterations to choices of metabolic pathways from those in lymphocytes in healthy individuals. This article provides an overview of metabolic pathways required for energy generation during homeostasis and those induced during cellular differentiation and responses. Furthermore, we explore available evidence for altered metabolic pathway induction in some autoimmune diseases. A focus of the overview will be on helper T lymphocytes involved in chronic inflammation and those that regulate the immune response. The report alludes to the potential that targeting metabolic pathways could provide a strategy for the treatment of chronic diseases.

/pdf/metabolic-pathways-underpinning-lymphocyte-differentiation-1pkgz4aa6s.pdf

Isabella Atzeni

Papers

A 3D approach to the archaeological study of the built remains at the Santa Cristina well sanctuary, Sardinia, Italy