Author
Isao Tanaka
Other affiliations: Nagoya University
Bio: Isao Tanaka is an academic researcher from Max Planck Society. The author has contributed to research in topics: Ribosomal protein & Ribosome. The author has an hindex of 4, co-authored 4 publications receiving 342 citations. Previous affiliations of Isao Tanaka include Nagoya University.
Papers
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TL;DR: The 3-Å structure of DNA-binding protein II, which exhibits histone-like properties in bacteria, has been determined and a mechanism by which the protein induces DNA supercoiling is proposed.
Abstract: The 3-A structure of DNA-binding protein II, which exhibits histone-like properties in bacteria, has been determined. The molecule is dimeric and appears to bind to the phosphate backbone of DNA through two symmetry-related arms. A mechanism by which the protein induces DNA supercoiling is proposed.
308 citations
TL;DR: The low‐M r proteins (tentatively called protein I and II) were purified from 2 M NaCl extracts of the Bacillus stearothermophilus ribosome and shows significant similarity to L32 from E. coli, whereas that of protein II is slightly, if at all, related to ribosomal protein L34 from E coli.
16 citations
TL;DR: The structure of protein L6 from the large subunit of the Bacillus stearothermophilus ribosome is described at a nominal resolution of 6 Å and appears to be compact, with an axial ratio significantly below 2:1.
11 citations
TL;DR: The structure of DNA binding protein II from Bacillus stearothermophilus is described at 6 Å resolution and there are 3 independent dimers related by non‐crystallographic symmetry in the unit cell.
8 citations
Cited by
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TL;DR: A cDNA clone that codes for a new tissue-specific DNA binding protein, PU.1, was isolated and was shown to be a transcriptional activator that is expressed in macrophages and B cells.
923 citations
TL;DR: DNA bending induced by the H MG domain can facilitate the formation of higher-order nucleoprotein complexes, suggesting that HMG domain proteins may have an architectural role in assembling such complexes.
804 citations
TL;DR: The crystal structure of IHF complexed with 35 bp of DNA is reported, providing evidence for the importance of a narrow minor groove in IHF's binding sequence.
780 citations
702 citations
TL;DR: Human CTF/NF-I consists of a family of CCAAT box binding proteins that activate both transcription and DNA replication and analysis of cDNA mutants reveals that the N-terminal portion of CTF-1 is sufficient for site-specific DNA recognition, protein dimerization, and adenovirus replication.
701 citations