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Istvan Albert
Researcher at Pennsylvania State University
Publications - 108
Citations - 15177
Istvan Albert is an academic researcher from Pennsylvania State University. The author has contributed to research in topics: Gene & Biology. The author has an hindex of 40, co-authored 97 publications receiving 13080 citations. Previous affiliations of Istvan Albert include University of Minnesota & University of Notre Dame.
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Galaxy: A platform for interactive large-scale genome analysis
Belinda Giardine,Cathy Riemer,Ross C. Hardison,Richard Burhans,Laura Elnitski,Prachi Shah,Prachi Shah,Yi Zhang,Daniel Blankenberg,Istvan Albert,James Taylor,Webb Miller,W. James Kent,Anton Nekrutenko +13 more
TL;DR: An interactive system, Galaxy, that combines the power of existing genome annotation databases with a simple Web portal to enable users to search remote resources, combine data from independent queries, and visualize the results.
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Nivolumab plus Ipilimumab in Advanced Non-Small-Cell Lung Cancer.
Matthew D. Hellmann,Luis Paz-Ares,Reyes Bernabe Caro,B. Zurawski,Sang-We Kim,Enric Carcereny Costa,Keunchil Park,A. Alexandru,L. Lupinacci,Emmanuel de la Mora Jimenez,Hiroshi Sakai,Istvan Albert,Alain Vergnenegre,Solange Peters,Konstantinos N. Syrigos,Fabrice Barlesi,Martin Reck,Hossein Borghaei,Julie R. Brahmer,Kenneth J. O'Byrne,William J. Geese,Prabhu Bhagavatheeswaran,Sridhar K. Rabindran,Ravi S. Kasinathan,F. E. Nathan,Suresh S. Ramalingam +25 more
TL;DR: First-line treatment with nivolumab plus ipilimumab resulted in a longer duration of overall survival than did chemotherapy in patients with NSCLC, independent of the PD-L1 expression level.
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Structural vulnerability of the North American power grid
TL;DR: The power grid is robust to most perturbations, yet disturbances affecting key transmission substations greatly reduce its ability to function, and it is emphasized that the global properties of the underlying network must be understood as they greatly affect local behavior.
Journal ArticleDOI
Nucleosome organization in the Drosophila genome
Travis N. Mavrich,Cizhong Jiang,Ilya Ioshikhes,Xiao-Yong Li,Bryan J. Venters,Sara J. Zanton,Lynn P. Tomsho,Ji Qi,Robert L. Glaser,Stephan C. Schuster,David S. Gilmour,Istvan Albert,B. Franklin Pugh +12 more
TL;DR: A high-resolution reference map of H2A.Z and bulk nucleosome locations across the genome of the fly Drosophila melanogaster is produced and that from the yeast Saccharomyces cerevisiae is compared.
Journal ArticleDOI
Translational and rotational settings of H2A.Z nucleosomes across the Saccharomyces cerevisiae genome
Istvan Albert,Travis N. Mavrich,Lynn P. Tomsho,Ji Qi,Sara J. Zanton,Stephan C. Schuster,B. Franklin Pugh +6 more
TL;DR: The sequence of 322,000 individual Saccharomyces cerevisiae nucleosomes, containing the histone variant H2A.Z, reveals an intimate relationship between chromatin architecture and the underlying DNA sequence it regulates.