scispace - formally typeset
I

Istvan Lekli

Researcher at University of Debrecen

Publications -  70
Citations -  7748

Istvan Lekli is an academic researcher from University of Debrecen. The author has contributed to research in topics: Autophagy & Resveratrol. The author has an hindex of 29, co-authored 65 publications receiving 7069 citations. Previous affiliations of Istvan Lekli include University of Connecticut & University of Connecticut Health Center.

Papers
More filters
Journal ArticleDOI

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
Journal ArticleDOI

Cardioprotection by resveratrol: a novel mechanism via autophagy involving the mTORC2 pathway.

Narasimman Gurusamy, +7 more
- 01 Apr 2010 - 
TL;DR: The results indicate that at lower dose, resveratrol-mediated cell survival is, in part, mediated through the induction of autophagy involving the mTOR-Rictor survival pathway.
Journal ArticleDOI

Cardioprotection by adaptation to ischaemia augments autophagy in association with BAG-1 protein.

Narasimman Gurusamy, +5 more
- 01 Feb 2009 - 
TL;DR: Results clearly indicate that myocardial protection elicited by adaptation is mediated at least in part via up‐regulation of autophagy in association with BAG‐1 protein.
Journal ArticleDOI

Redox regulation of cell survival by the thioredoxin superfamily: an implication of redox gene therapy in the heart.

Md. Kaimul Ahsan, +4 more
- 15 Oct 2009 - 
TL;DR: Members of the thioredoxin superfamily, along with their isoforms, are involved in interaction with the members of metabolic and signaling pathways, thus making them attractive targets for clinical intervention and raising the hope for possible gene therapy as modern genetic medicine.
Journal ArticleDOI

Expression of the longevity proteins by both red and white wines and their cardioprotective components, resveratrol, tyrosol, and hydroxytyrosol.

Subhendu Mukherjee, +4 more
- 01 Mar 2009 - 
TL;DR: White wine and its cardioprotective components possess anti-aging properties by feeding rats with resveratrol andhydroxytyrosol, suggesting the existence of different signaling mechanisms for the induction of longevity and survival.