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Ivone Carvalho
Researcher at University of São Paulo
Publications - 106
Citations - 3895
Ivone Carvalho is an academic researcher from University of São Paulo. The author has contributed to research in topics: Trypanosoma cruzi & Acetylcholinesterase. The author has an hindex of 25, co-authored 103 publications receiving 3397 citations. Previous affiliations of Ivone Carvalho include University of East Anglia & University of St Andrews.
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Carrageenans: biological properties, chemical modifications and structural analysis - a review.
TL;DR: This review describes important aspects of carrageenans related to their industrial/therapeutic applications, physicochemical properties and structural analysis and indicates that these polysaccharides may offer some protection against HIV infection.
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α- and β-Glucosidase inhibitors: chemical structure and biological activity
TL;DR: This review is aimed at highlighting the main chemical classes of glucosidase inhibitors, as well as their biological activities toward α- and β-glucosidases, but it is not intended to be an exhaustive review on the subject.
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Diketopiperazines : biological activity and synthesis
TL;DR: The biological properties of disubstituted 2,5-diketopiperazines and the corresponding synthetic procedures that allow the generation of large arrays of derivatives with interesting biological applications are described.
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Application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) ‘click chemistry’ in carbohydrate drug and neoglycopolymer synthesis
Valquiria Aragão-Leoneti,Vanessa Leiria Campo,Adriane da Silveira Gomes,Robert A. Field,Ivone Carvalho +4 more
TL;DR: An overview of the potential application of copper(I)-catalysed azide/alkyne cycloaddition (CuAAC) ‘click chemistry’ in the synthesis of bioactive carbohydrates and neoglycopolymers is described.
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'Click chemistry' synthesis of a library of 1,2,3-triazole-substituted galactose derivatives and their evaluation against Trypanosoma cruzi and its cell surface trans-sialidase.
Ivone Carvalho,Peterson de Andrade,Vanessa Leiria Campo,Paulo Marcos da Matta Guedes,Renata Sesti-Costa,João Santana da Silva,Sergio Schenkman,Simone Dedola,Lionel Hill,Martin Rejzek,Sergey A. Nepogodiev,Robert A. Field +11 more
TL;DR: In vitro trypanocidal activity assays against the trypomastigote form of T. cruzi Y strain revealed several compounds active in the low 100s of muM range, which suggests a specific mode of anti-parasite action rather than a generic cytotoxic effect.