J
J. C. van Swieten
Researcher at Erasmus University Rotterdam
Publications - 104
Citations - 17713
J. C. van Swieten is an academic researcher from Erasmus University Rotterdam. The author has contributed to research in topics: Frontotemporal dementia & Dementia. The author has an hindex of 46, co-authored 104 publications receiving 16377 citations. Previous affiliations of J. C. van Swieten include VU University Amsterdam & Mayo Clinic.
Papers
More filters
Journal ArticleDOI
Interobserver agreement for the assessment of handicap in stroke patients.
TL;DR: The results confirm the value of the modified Rankin scale in the assessment of handicap in stroke patients; nevertheless, further improvements are possible.
Journal ArticleDOI
Association of missense and 5′-splice-site mutations in tau with the inherited dementia FTDP-17
Mike Hutton,Corinne Lendon,Patrizia Rizzu,Matt Baker,Susanne Froelich,Susanne Froelich,Henry Houlden,Stuart Pickering-Brown,Sumitra Chakraverty,Adrian M. Isaacs,Andrew Grover,J. Hackett,Jennifer Adamson,Sarah Lincoln,Dennis W. Dickson,Peter Davies,Ronald C. Petersen,M. Stevens,E. De Graaff,E. Wauters,J. Van Baren,M. Hillebrand,Marijke Joosse,J. M. Kwon,Petra Nowotny,Lien Kuei Che,Joanne Norton,John C. Morris,L. A. Reed,John Q. Trojanowski,Hans Basun,Lars Lannfelt,M. Neystat,Stanley Fahn,Frances Dark,Tony Tannenberg,Peter R. Dodd,Nicholas K. Hayward,John B.J. Kwok,Peter R. Schofield,Athena Andreadis,Julie S. Snowden,David Craufurd,David Neary,F. Owen,Ben A. Oostra,John Hardy,Alison Goate,J. C. van Swieten,David M. A. Mann,Timothy Lynch,Peter Heutink +51 more
TL;DR: In this paper, the authors sequenced tau in FTDP-17 families and identified three missense mutations (G272V, P301L and R406W) and three mutations in the 5' splice site of exon in
Journal ArticleDOI
Cerebral white matter lesions, vascular risk factors, and cognitive function in a population‐based study The Rotterdam Study
Monique M.B. Breteler,J. C. van Swieten,M. L. Bots,D. E. Grobbee,J. J. Claus,J. H. W. Van Den Hout,F. van Harskamp,Hervé L. J. Tanghe,P.T.V.M. de Jong,J. van Gijn,Albert Hofman +10 more
TL;DR: In this article, the prevalence of white matter lesions and their relation with classic cardiovascular risk factors, thrombogenic factors, and cognitive function in an age and gender-stratified random sample from the general population were studied.
Journal ArticleDOI
Periventricular lesions in the white matter on magnetic resonance imaging in the elderly. A morphometric correlation with arteriolosclerosis and dilated perivascular spaces
J. C. van Swieten,J. H. W. Van Den Hout,B. A. Van Ketel,A. Hijdra,J. H. J. Wokke,J. van Gijn +5 more
TL;DR: The findings suggest that arteriolosclerosis is the primary factor in the pathogenesis of diffuse white matter lesions in the elderly, soon followed by demyelination and loss of axons, and only later by dilatation of perivascular spaces.
Journal ArticleDOI
DJ-1( PARK7), a novel gene for autosomal recessive, early onset parkinsonism.
Vincenzo Bonifati,Vincenzo Bonifati,Patrizia Rizzu,Ferdinando Squitieri,Elmar Krieger,Nicola Vanacore,J. C. van Swieten,Alexis Brice,C M van Duijn,Ben A. Oostra,Giuseppe Meco,Peter Heutink +11 more
TL;DR: Evidence from genetic studies on the yeast DJ-1 homologue, and biochemical studies in murine and human cell lines, suggests a role forDJ-1 as an antioxidant and/or a molecular chaperone, and this will lead to a better understanding of the pathogenesis of DJ- 1-related and common forms of Parkinson’s disease.