J. G. Banwell

Bio: J. G. Banwell is an academic researcher. The author has contributed to research in topics: Malabsorption & Serum albumin. The author has an hindex of 5, co-authored 6 publications receiving 197 citations.

An investigation of tropical splenomegaly at mulago hospital, kampala, uganda.

Abstract: helpful advice and valuable criticism. I am also indebted to Professor Mary Barber, Postgraduate Medical School, London ; Dr. Jean Bradley, Fulham Hospital, London ; Dr. J. H. Darrell, Post graduate Medical School, London ; Professor A. El Ghoroury, Institute of Hygiene, Alexandria ; Dr. E. J. L. Lowbury, M.R.C. Industrial Injuries and Burns Research Unit, Birmingham ; Dr. Joan McWilliam, Royal Infirmary, Edinburgh ; Dr. L. Parker, Booth Hall Hospital, Manchester ; Dr. K. B. Rogers, the Children's Hospital, Birmingham ; Dr. J. K. Sch?nfeld, Rotterdam ; Professor R. A. Shooter, St. Bartholomew's Hospital Medical School, London ; Dr. M. Veron, Institut Pasteur, Paris ; and Dr. Josephine A. C. Weatherall, Charing Cross Hospital, London, for sending strains and showing interest in this work. REFERENCES

Exocrine pancreatic disease and the malabsorption syndrome in tropical Africa.

Abstract: EDITORIAL, COMMENT The study of malabsorption in Uganda, East Africa, has revealed that the majority of patients who have steatorrhoea suffer from exocrine pancreatic disorders. The differing incidence of malabsorption syndromes in a hospital community in Kampala, Uganda, has been compared with the incidence in both temperate and tropical climates and the clinical and laboratory features of this syndrome are discussed.

Albumin metabolism in hookworm anaemias.

Abstract: 17 patients infected with hookworms were used in a study of albumin metabolism and faecal albumin loss. They were compared with 9 controls. Factors relating to the use of 131 I-labelled albumin as a measure of albumin metabolism are discussed. Some doubt has recently been expressed as to whether faecal activity appearing in this method represents wholly albumin breakdown in or near the gut, or partly endogenous breakdown with subsequent secretion of iodide. The weight of evidence has indicated the former. The method of measuring salivary excretion of iodide and its fate may need elaborating. There seems to be little division of opinion about the bowel origin of excessive albumin losses. It is claimed that hookworm patients lose excessive albumin into their gut. The loss of albumin is roughly 0·1 g. per 100 hookworms of the species Necator americanus . This is equivalent to the loss of 3 ml. plasma per 100 hookworms. This figure agrees very well with other published work based on red cell losses estimated by 51 Cr. There seems to be a satisfactory correlation between albumin and plasma losses on the one hand, and numbers of hookworms harboured on the other. Female hookworms were in the preponderance (ratio 3 : 2). In Kampala only N. americanus was found. The worms were themselves devoid of radio-activity.

Micro-analysis in medical biochemistry

Abstract: This booklet aims at giving what is necessary for understanding and undertaking chemical analysis for clinical purposes of materials for the body. Many of the included items (such as, under urine, Rothera's test and Gerhardt's test for ' acetoneand tests for albumen and bile pigment) are not really analyses but qualitative tests. Faults characteristic of hasty proof reading are noticeable. There is an ineonsistency in regarding quantities as singular or plural : ' Five mil. of Benedict's

Criteria of case definition in Crohn's disease and ulcerative colitis.

Abstract: The diagnosis of inflammatory bowel disease is usually made on a combination of clinical, radiologic, endoscopic, and histologic grounds. In the differential diagnosis, endoscopy and histologic evaluation of biopsy specimens can help to make a specific diagnosis. Site of disease is important in documentation and can determine drug choice and clinical course. Disease activity indices are important to assess a patient objectively, particularly in multicentre studies. There is poor correlation between disease activity indices and macroscopic and histologic findings. The Severity Activity Index for Crohn's disease has both clinical and laboratory variables and is a valuable tool for the definition of Crohn's disease. An ulcerative colitis activity index that correlates significantly with microscopic and macroscopic scores, using both clinical symptoms and laboratory findings, is proposed.

NZW x BXSB)F1 hybrid. A model of acute lupus and coronary vascular disease with myocardial infarction.

Abstract: Both sexes of the (NZW x BXSB)F1 mice developed an early systemic lupus erythematosus-like disease. In males, the disease resembled that in the BXSB male parent and was not affected by sex hormonal manipulation. In females, the disease duplicated that of (NZB x NZW)F1 females by virtue of a delayed onset and estrogen dependence. Autoantibody production, circulating Ig-bound gp 70 immune complexes, and deposition of Ig and gp 70 in the affected glomeruli were demonstrated in both males and females. The abnormally high incidence of degenerative coronary vascular disease with myocardial infarction, particularly in these F1 males, provides a useful model for the investigation of a possible immunologic component in coronary vascular disease.