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J. K. Blodgett

Bio: J. K. Blodgett is an academic researcher. The author has contributed to research in topics: (Bis(trifluoroacetoxy)iodo)benzene. The author has an hindex of 1, co-authored 1 publications receiving 155 citations.

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Journal ArticleDOI
TL;DR: In assays of the human matrix metalloproteinases, Mca‐Pro‐ Leu‐Gly‐Leu‐Dpa‐Ala‐Arg‐NH2 is about 50 to 100 times more sensitive than dinitrophenyl‐Pro •Leu •Gly •LeU‐Trp •Ala •d‐Arg •NH2 and continuous assays can be made at enzyme concentrations comparable to those used with macromolecular substrates.

739 citations

Journal ArticleDOI
TL;DR: The large diversity of high-yielding and chemoselective reactions that can be achieved, even for highly functionalized molecules, is summarized, demonstrating that hypervalent iodine reagents have become an essential tool in synthetic organic chemistry.

245 citations

Patent
21 Aug 2006
TL;DR: In this article, a method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided, which can be used to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a cross linked medical device coating.
Abstract: A method for making a medical device having at least one biomolecule immobilized on a substrate surface is provided. One method of the present invention includes immobilizing a biomolecule comprising an unsubstituted amide moiety on a biomaterial surface. Another method of the present invention includes immobilizing a biomolecule on a biomaterial surface comprising an unsubstituted amide moiety. Still another method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties immobilized on medical device surfaces. Additionally, one method of the present invention may be employed to crosslink biomolecules comprising unsubstituted amide moieties in solution, thereby forming a crosslinked biomaterial or a crosslinked medical device coating.

188 citations

Journal ArticleDOI
TL;DR: In this article, an efficient, general procedure for highly chemoselective reductive mono-alkylation of ammonia with ketones is reported, followed by in situ sodium borohydride reduction, and a straightforward workup afforded primary amines in good yield.

150 citations