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J. Sijbers

Bio: J. Sijbers is an academic researcher. The author has contributed to research in topics: Automatic frequency control. The author has an hindex of 1, co-authored 2 publications receiving 228 citations.


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Journal ArticleDOI
TL;DR: An insight into the analogies, state-of-the-art technologies, concepts, and prospects under the umbrella of perovskite materials (both inorganic-organic hybrid halideperovskites and ferroelectric perovkites) for future multifunctional energy conversion and storage devices is provided.
Abstract: An insight into the analogies, state-of-the-art technologies, concepts, and prospects under the umbrella of perovskite materials (both inorganic-organic hybrid halide perovskites and ferroelectric perovskites) for future multifunctional energy conversion and storage devices is provided. Often, these are considered entirely different branches of research; however, considering them simultaneously and holistically can provide several new opportunities. Recent advancements have highlighted the potential of hybrid perovskites for high-efficiency solar cells. The intrinsic polar properties of these materials, including the potential for ferroelectricity, provide additional possibilities for simultaneously exploiting several energy conversion mechanisms such as the piezoelectric, pyroelectric, and thermoelectric effect and electrical energy storage. The presence of these phenomena can support the performance of perovskite solar cells. The energy conversion using these effects (piezo-, pyro-, and thermoelectric effect) can also be enhanced by a change in the light intensity. Thus, there lies a range of possibilities for tuning the structural, electronic, optical, and magnetic properties of perovskites to simultaneously harvest energy using more than one mechanism to realize an improved efficiency. This requires a basic understanding of concepts, mechanisms, corresponding material properties, and the underlying physics involved with these effects.

1,015 citations

Journal ArticleDOI
10 Sep 2015-Nature
TL;DR: A model for tumour evolution is described that shows how short-range dispersal and cell turnover can account for rapid cell mixing inside the tumour, and shows that even a small selective advantage of a single cell within a large tumour allows the descendants of that cell to replace the precursor mass in a clinically relevant time frame.
Abstract: Most cancers in humans are large, measuring centimetres in diameter, and composed of many billions of cells. An equivalent mass of normal cells would be highly heterogeneous as a result of the mutations that occur during each cell division. What is remarkable about cancers is that virtually every neoplastic cell within a large tumour often contains the same core set of genetic alterations, with heterogeneity confined to mutations that emerge late during tumour growth. How such alterations expand within the spatially constrained three-dimensional architecture of a tumour, and come to dominate a large, pre-existing lesion, has been unclear. Here we describe a model for tumour evolution that shows how short-range dispersal and cell turnover can account for rapid cell mixing inside the tumour. We show that even a small selective advantage of a single cell within a large tumour allows the descendants of that cell to replace the precursor mass in a clinically relevant time frame. We also demonstrate that the same mechanisms can be responsible for the rapid onset of resistance to chemotherapy. Our model not only provides insights into spatial and temporal aspects of tumour growth, but also suggests that targeting short-range cellular migratory activity could have marked effects on tumour growth rates.

457 citations

Journal ArticleDOI
TL;DR: Optical Whispering Gallery Modes (WGMs) derive their name from a famous acoustic phenomenon of guiding a wave by a curved boundary observed nearly a century ago as mentioned in this paper, which enables resonators of unique properties attractive both in science and engineering.
Abstract: Optical Whispering Gallery Modes (WGMs) derive their name from a famous acoustic phenomenon of guiding a wave by a curved boundary observed nearly a century ago. This phenomenon has a rather general nature, equally applicable to sound and all other waves. It enables resonators of unique properties attractive both in science and engineering. Very high quality factors of optical WGM resonators persisting in a wide wavelength range spanning from radio frequencies to ultraviolet light, their small mode volume, and tunable in- and out- coupling make them exceptionally efficient for nonlinear optical applications. Nonlinear optics facilitates interaction of photons with each other and with other physical systems, and is of prime importance in quantum optics. In this paper we review numerous applications of WGM resonators in nonlinear and quantum optics. We outline the current areas of interest, summarize progress, highlight difficulties, and discuss possible future development trends in these areas.

231 citations

Journal ArticleDOI
TL;DR: Different approaches to the realization of FBARs, SAW resonators and SAW delay lines for various biochemical applications are presented and methods of integration of the acoustic wave MEMS devices in the microfluidic systems and functionalization strategies will be discussed.

207 citations

Journal ArticleDOI
TL;DR: This work demonstrates synchronization in arrays of silicon nitride micromechanical oscillators coupled in an all-to-all configuration purely through an optical radiation field and shows that the phase noise of the synchronized oscillators can be improved by almost 10 dB below the phase Noise limit for each individual oscillator.
Abstract: Synchronization of many coupled oscillators is widely found in nature and has the potential to revolutionize timing technologies. Here, we demonstrate synchronization in arrays of silicon nitride micromechanical oscillators coupled in an all-to-all configuration purely through an optical radiation field. We show that the phase noise of the synchronized oscillators can be improved by almost 10 dB below the phase noise limit for each individual oscillator. These results open a practical route towards synchronized oscillator networks.

178 citations