J
J.T. Mitchell
Researcher at Myriad Genetics
Publications - 9
Citations - 8159
J.T. Mitchell is an academic researcher from Myriad Genetics. The author has contributed to research in topics: Genome & Shotgun sequencing. The author has an hindex of 8, co-authored 9 publications receiving 7720 citations.
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Journal ArticleDOI
A draft sequence of the rice genome (Oryza sativa L. ssp indica)
Stephen A. Goff,Darrell O. Ricke,Tien-Hung Lan,Gernot G. Presting,Ronglin Wang,Molly Dunn,Jane Glazebrook,Allen Sessions,Paul Oeller,Hemant Varma,David Hadley,Don Hutchison,Christopher M. Martin,Fumiaki Katagiri,B. Markus Lange,Todd Moughamer,Yu Xia,Paul Budworth,Jingping Zhong,Trini Miguel,Uta Paszkowski,Shiping Zhang,Michelle Colbert,Wei-lin Sun,Lili Chen,Bret Cooper,Sylvia Park,Todd Charles Wood,Long Mao,Peter H. Quail,Rod A. Wing,Ralph A. Dean,Yeisoo Yu,Andrey Zharkikh,Richard Shen,Sudhir Sahasrabudhe,Alun Thomas,Rob Cannings,Alexander Gutin,Dmitry Pruss,Julia Reid,Sean V. Tavtigian,J.T. Mitchell,Glenn Eldredge,Terri Scholl,Rose Mary Miller,Satish Bhatnagar,Nils Adey,Todd Rubano,Nadeem Tusneem,Rosann Robinson,Jane Feldhaus,Teresita Macalma,Arnold R. Oliphant,Steven P. Briggs +54 more
TL;DR: A draft sequence of the rice genome for the most widely cultivated subspecies in China, Oryza sativa L. ssp.indica, by whole-genome shotgun sequencing is produced, with a large proportion of rice genes with no recognizable homologs due to a gradient in the GC content of rice coding sequences.
Journal ArticleDOI
The genome of the domesticated apple ( Malus × domestica Borkh.)
Riccardo Velasco,Andrey Zharkikh,Jason P. Affourtit,Amit Dhingra,Alessandro Cestaro,Ananth Kalyanaraman,Paolo Fontana,Satish Bhatnagar,Michela Troggio,Dmitry Pruss,Silvio Salvi,Massimo Pindo,Paolo Baldi,Sara Castelletti,Marina Cavaiuolo,G. Coppola,Fabrizio Costa,V. Cova,Antonio Dal Ri,Vadim V. Goremykin,M. Komjanc,Sara Longhi,P. Magnago,Giulia Malacarne,Mickael Malnoy,Diego Micheletti,Marco Moretto,Michele Perazzolli,Azeddine Si-Ammour,Silvia Vezzulli,E. Zini,Glenn Eldredge,Lisa M. Fitzgerald,N. Gutin,Jerry S. Lanchbury,Teresita Macalma,J.T. Mitchell,Julia Reid,Bryan Wardell,Chinnappa D. Kodira,Zhoutao Chen,Brian Desany,Faheem Niazi,Melinda Palmer,Tyson Koepke,Derick Jiwan,Scott Schaeffer,Vandhana Krishnan,Changjun Wu,Vu T. Chu,Stephen T. King,Jessica Vick,Quanzhou Tao,Amy Mraz,Aimee Stormo,Keith E. Stormo,Robert Bogden,Davide Ederle,Alessandra Stella,Alberto Vecchietti,Martin M. Kater,Simona Masiero,Pauline Lasserre,Yves Lespinasse,Andrew C. Allan,Vincent G. M. Bus,David Chagné,Ross N. Crowhurst,Andrew P. Gleave,Enrico Lavezzo,Jeffrey A. Fawcett,Jeffrey A. Fawcett,Sebastian Proost,Sebastian Proost,Pierre Rouzé,Pierre Rouzé,Lieven Sterck,Lieven Sterck,Stefano Toppo,Barbara Lazzari,Roger P. Hellens,Charles-Eric Durel,Alexander Gutin,Roger E. Bumgarner,Susan E. Gardiner,Mark H. Skolnick,Michael Egholm,Yves Van de Peer,Yves Van de Peer,Francesco Salamini,Roberto Viola +90 more
TL;DR: It is shown that a relatively recent (>50 million years ago) genome-wide duplication has resulted in the transition from nine ancestral chromosomes to 17 chromosomes in the Pyreae, which partly support the monophyly of the ancestral paleohexaploidy of eudicots.
Journal ArticleDOI
A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety
Riccardo Velasco,Andrey Zharkikh,Michela Troggio,Dustin Cartwright,Alessandro Cestaro,Dmitry Pruss,Massimo Pindo,Lisa M. Fitzgerald,Silvia Vezzulli,Julia Reid,Giulia Malacarne,Diana Iliev,G. Coppola,Bryan Wardell,Diego Micheletti,Teresita Macalma,Marco Facci,J.T. Mitchell,Michele Perazzolli,Glenn Eldredge,Pamela Gatto,Rozan Oyzerski,Marco Moretto,N. Gutin,Marco Stefanini,Yang Chen,C. Segala,Christine Davenport,Lorenzo Dematte,Amy Mraz,Juri Battilana,Keith E. Stormo,Fabrizio Costa,Quanzhou Tao,Azeddine Si-Ammour,Tim Harkins,Angie Lackey,Clotilde Perbost,Bruce E Taillon,Alessandra Stella,Victor V. Solovyev,Jeffrey A. Fawcett,Lieven Sterck,Klaas Vandepoele,Stella M. Grando,Stefano Toppo,Claudio Moser,Jerry S. Lanchbury,Robert Bogden,Mark H. Skolnick,Vittorio Sgaramella,Satish Bhatnagar,Paolo Fontana,Alexander Gutin,Yves Van de Peer,Francesco Salamini,Roberto Viola +56 more
TL;DR: A high quality draft genome sequence of a cultivated clone of V. vinifera Pinot Noir provides candidate genes implicated in traits relevant to grapevine cultivation, such as those influencing wine quality, via secondary metabolites, and those connected with the extreme susceptibility of grape to pathogens.
Journal ArticleDOI
The complete BRCA2 gene and mutations in chromosome 13q-linked kindreds.
Sean V. Tavtigian,Jacques Simard,Johanna M. Rommens,Fergus J. Couch,Donna M Shattuck-Eidens,Susan L. Neuhausen,Sofia D. Merajver,Steinunn Thorlacius,Kenneth Offit,Dominique Stoppa-Lyonnet,Carole Bélanger,Russell Bell,Simin Berry,Robert Bogden,Qian Chen,Thaylon Davis,Martine Dumont,Cheryl Frye,T. Hattier,Srikanth Jammulapati,Teresa Janecki,Ping Jiang,Robert Kehrer,J.-F. Leblanc,J.T. Mitchell,Jodi Mcarthur-Morrison,K. Nguyen,Yi Peng,Chantal Samson,Marianne Schroeder,S.C. Snyder,Linda Steele,M. Stringfellow,C. Stroup,Bradley D. Swedlund,J. Swense,David H. F. Teng,Alun Thomas,T.D. Tran,Martine Tranchant,Jane Weaver-Feldhaus,Alexander K. C. Wong,Hiroaki Shizuya,Jorunn E. Eyfjord,Lisa A. Cannon-Albright,Fernand Labrie,Mark H. Skolnick,Mark H. Skolnick,Barbara L. Weber,Alexander Kamb,David E. Goldgar,David E. Goldgar +51 more
TL;DR: The complete coding sequence and exonic structure of BRCA2 is determined, and its pattern of expression is examined, and a mutational analysis of B RCA2 in families selected on the basis of linkage analysis and/or the presence of one or more cases of male breast cancer is reported.
Journal Article
Human Mitogen-activated Protein Kinase Kinase 4 as a Candidate Tumor Suppressor
David H. F. Teng,William L. Perry,James K. Hogan,Michelle Baumgard,Russell Bell,Simin Berry,Thaylon Davis,David A. Frank,Cheryl Frye,T. Hattier,Rong Hu,Srikanth Jammulapati,Teresa Janecki,Amber Leavitt,J.T. Mitchell,Ralph Pero,David Sexton,Marianne Schroeder,Pi Hsia Su,Brad Swedlund,John M. Kyriakis,Joseph Avruch,Paul L. Bartel,Alexander K. C. Wong,Arnold R. Oliphant,Alun Thomas,Mark H. Skolnick,Sean V. Tavtigian +27 more
TL;DR: Findings suggest that MKK4 may function as a suppressor of tumorigenesis or metastasis in certain types of cells.