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Jacob Bak Holm

Researcher at University of Copenhagen

Publications -  26
Citations -  2870

Jacob Bak Holm is an academic researcher from University of Copenhagen. The author has contributed to research in topics: Microbiome & Medicine. The author has an hindex of 18, co-authored 20 publications receiving 1968 citations.

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Human gut microbes impact host serum metabolome and insulin sensitivity

TL;DR: It is shown how the human gut microbiome impacts the serum metabolome and associates with insulin resistance in 277 non-diabetic Danish individuals and suggested that microbial targets may have the potential to diminish insulin resistance and reduce the incidence of common metabolic and cardiovascular disorders.
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Physiological role of taurine--from organism to organelle.

TL;DR: Taurine homeostasis in cells and organelles is described with emphasis on taurine biophysics/membrane dynamics, regulation of transport proteins involved in active and passive t aurine release as well as physiological processes, for example, development, lung function, mitochondrial function, antioxidative defence and apoptosis which seem to be affected by a shift in the expression of the taurin transporters and/or the cellular taurines.
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Chronic Trichuris muris Infection Decreases Diversity of the Intestinal Microbiota and Concomitantly Increases the Abundance of Lactobacilli.

TL;DR: The results demonstrate that chronic parasite infection strongly influences the intestinal microbiota and the adaptive immune system, and illustrate the complex interactions between these factors in the intestinal tract, and contribute to furthering the understanding of this interplay.