J
Jacob Odeberg
Researcher at Royal Institute of Technology
Publications - 125
Citations - 16901
Jacob Odeberg is an academic researcher from Royal Institute of Technology. The author has contributed to research in topics: Gene & Gene expression. The author has an hindex of 35, co-authored 119 publications receiving 12450 citations. Previous affiliations of Jacob Odeberg include Uppsala University & University of Tromsø.
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Journal ArticleDOI
Tissue-based map of the human proteome
Mathias Uhlén,Mathias Uhlén,Linn Fagerberg,Björn M. Hallström,Cecilia Lindskog,Per Oksvold,Adil Mardinoglu,Åsa Sivertsson,Caroline Kampf,Evelina Sjöstedt,Evelina Sjöstedt,Anna Asplund,IngMarie Olsson,Karolina Edlund,Emma Lundberg,Sanjay Navani,Cristina Al-Khalili Szigyarto,Jacob Odeberg,Dijana Djureinovic,Jenny Ottosson Takanen,Sophia Hober,Tove Alm,Per-Henrik Edqvist,Holger Berling,Hanna Tegel,Jan Mulder,Johan Rockberg,Peter Nilsson,Jochen M. Schwenk,Marica Hamsten,Kalle von Feilitzen,Mattias Forsberg,Lukas Persson,Fredric Johansson,Martin Zwahlen,Gunnar von Heijne,Jens Nielsen,Jens Nielsen,Fredrik Pontén +38 more
TL;DR: In this paper, a map of the human tissue proteome based on an integrated omics approach that involves quantitative transcriptomics at the tissue and organ level, combined with tissue microarray-based immunohistochemistry, to achieve spatial localization of proteins down to the single-cell level.
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Analysis of the human tissue-specific expression by genome-wide integration of transcriptomics and antibody-based proteomics
Linn Fagerberg,Björn M. Hallström,Per Oksvold,Caroline Kampf,Dijana Djureinovic,Jacob Odeberg,Masato Habuka,Simin Tahmasebpoor,Angelika Danielsson,Karolina Edlund,Anna Asplund,Evelina Sjöstedt,Emma Lundberg,Cristina Al-Khalili Szigyarto,Marie Skogs,Jenny Ottosson Takanen,Holger Berling,Hanna Tegel,Jan Mulder,Peter Nilsson,Jochen M. Schwenk,Cecilia Lindskog,Frida Danielsson,Adil Mardinoglu,Åsa Sivertsson,Kalle von Feilitzen,Mattias Forsberg,Martin Zwahlen,IngMarie Olsson,Sanjay Navani,Mikael Huss,Jens Nielsen,Jens Nielsen,Fredrik Pontén,Mathias Uhlén +34 more
TL;DR: A quantitative transcriptomics analysis (RNA-Seq) is used to classify the tissue-specific expression of genes across a representative set of all major human organs and tissues and combined this analysis with antibody-based profiling of the same tissues.
Journal ArticleDOI
The human gene FALL39 and processing of the cathelin precursor to the antibacterial peptide LL-37 in granulocytes
Gudmundur H. Gudmundsson,Gudmundur H. Gudmundsson,Birgitta Agerberth,Birgitta Agerberth,Jacob Odeberg,Tomas Bergman,Berit Olsson,Rosalba Salcedo +7 more
TL;DR: The results indicate that FALL39 is the only member of the cathelin gene family present in the human genome and a possible role for the cytokine interleukin-6 in the regulation of FALL 39 is discussed.
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A single-cell type transcriptomics map of human tissues.
Max J. Karlsson,Cheng Zhang,Loren Méar,Wen Zhong,Andreas Digre,Borbala Katona,Evelina Sjöstedt,Lynn M. Butler,Jacob Odeberg,Philip Dusart,Fredrik Edfors,Per Oksvold,Kalle von Feilitzen,Martin Zwahlen,Muhammad Arif,Ozlem Altay,Xiangyu Li,Mehmet Ozcan,Adil Mardinoglu,Linn Fagerberg,Jan Mulder,Yonglun Luo,Fredrik Pontén,Mathias Uhlén,Mathias Uhlén,Cecilia Lindskog +25 more
TL;DR: In this article, the authors combined single-cell transcriptomics analysis with spatial antibody-based protein profiling to create a high-resolution singlecell type map of human tissues, which was used to explore the expression of human protein-coding genes in 192 individual cell type clusters.
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A genome-wide transcriptomic analysis of protein-coding genes in human blood cells
Mathias Uhlén,Mathias Uhlén,Mathias Uhlén,Max J. Karlsson,Wen Zhong,Abdellah Tebani,Christian Pou,Jaromír Mikeš,Tadepally Lakshmikanth,Björn Forsström,Fredrik Edfors,Jacob Odeberg,Jacob Odeberg,Adil Mardinoglu,Adil Mardinoglu,Cheng Zhang,Kalle von Feilitzen,Jan Mulder,Evelina Sjöstedt,Andreas Hober,Per Oksvold,Martin Zwahlen,Fredrik Pontén,Cecilia Lindskog,Åsa Sivertsson,Linn Fagerberg,Petter Brodin,Petter Brodin +27 more
TL;DR: The cellular distribution of genes known to cause primary immunodeficiencies in humans are shown and find that many of these genes are expressed in cells not currently implicated in these diseases, illustrating how this global atlas can help us better understand the function of specific genes across cells and tissues in humans.