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Jacqueline Imperial

Researcher at University of Chicago

Publications -  18
Citations -  3993

Jacqueline Imperial is an academic researcher from University of Chicago. The author has contributed to research in topics: Glucose tolerance test & Insulin. The author has an hindex of 18, co-authored 18 publications receiving 3757 citations. Previous affiliations of Jacqueline Imperial include University of Wisconsin-Madison.

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Prevalence of impaired glucose tolerance and diabetes in women with polycystic ovary syndrome.

TL;DR: It is concluded that women with PCOS should periodically have an OGTT and must be closely monitored for deterioration in glucose tolerance, particularly among those with IGT, the subgroup at highest risk for subsequent development of NIDDM.
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Sleep curtailment is accompanied by increased intake of calories from snacks.

TL;DR: Recurrent bedtime restriction can modify the amount, composition, and distribution of human food intake, and sleeping short hours in an obesity-promoting environment may facilitate the excessive consumption of energy from snacks but not meals.
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Troglitazone improves defects in insulin action, insulin secretion, ovarian steroidogenesis, and fibrinolysis in women with polycystic ovary syndrome.

TL;DR: The ability of the beta-cell to appropriately detect and respond to an oscillatory glucose infusion improved significantly after troglitazone treatment; the normalized spectral power for the insulin secretion rate increased to 5.9 +/- 1.1 and the marked reduction in PAI-1 could be expected to improve the fibrinolytic response to thrombosis in these subjects.
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Effects of metformin on insulin secretion, insulin action, and ovarian steroidogenesis in women with polycystic ovary syndrome

TL;DR: It is concluded that hyperinsulinemia and androgen excess in obese nondiabetic women with PCOS are not improved by the administration of metformin.
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Insufficient Sleep Undermines Dietary Efforts to Reduce Adiposity

TL;DR: The amount of human sleep contributes to the maintenance of fat-free body mass at times of decreased energy intake and Lack of sufficient sleep may compromise the efficacy of typical dietary interventions for weight loss and related metabolic risk reduction.