J
Jacqueline Marvel
Researcher at École normale supérieure de Lyon
Publications - 95
Citations - 6145
Jacqueline Marvel is an academic researcher from École normale supérieure de Lyon. The author has contributed to research in topics: Cytotoxic T cell & CD8. The author has an hindex of 37, co-authored 92 publications receiving 5462 citations. Previous affiliations of Jacqueline Marvel include French Institute of Health and Medical Research & University of Lyon.
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The XC chemokine receptor 1 is a conserved selective marker of mammalian cells homologous to mouse CD8α+ dendritic cells
Karine Crozat,Rachel Guiton,Rachel Guiton,Vanessa Contreras,Vincent Feuillet,Vincent Feuillet,Charles-Antoine Dutertre,Charles-Antoine Dutertre,Erwan Ventre,Erwan Ventre,Thien-Phong Vu Manh,Thien-Phong Vu Manh,Thomas Baranek,Thomas Baranek,Anne K. Storset,Jacqueline Marvel,Jacqueline Marvel,Pierre Boudinot,Anne Hosmalin,Anne Hosmalin,Isabelle Schwartz-Cornil,Marc Dalod,Marc Dalod +22 more
TL;DR: XCR1 constitutes the first conserved specific marker for cell subsets homologous to mouse CD8α+ DCs in higher vertebrates and promotes their ability to activate early CD8+ T cell defenses against an intracellular pathogenic bacteria.
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T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
Cécile Daussy,Fabrice Faure,Katia Mayol,Sébastien Viel,Georg Gasteiger,Emily Charrier,Jacques Bienvenu,Thomas Henry,Emilie Debien,Uzma Hasan,Jacqueline Marvel,Keigyou Yoh,Satoru Takahashi,Immo Prinz,Simon de Bernard,Laurent Buffat,Thierry Walzer +16 more
TL;DR: Mutually exclusive expression of T-bet and Eomes drives the development of distinct NK cell lineages with complementary functions.
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TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
Sébastien Viel,Antoine Marçais,Fernando Souza Fonseca Guimaraes,Fernando Souza Fonseca Guimaraes,Róisín M. Loftus,Jessica Rabilloud,Morgan Grau,Sophie Degouve,Sophia Djebali,Amélien Sanlaville,Emily Charrier,Jacques Bienvenu,Julien C. Marie,Julien C. Marie,Christophe Caux,Jacqueline Marvel,Liam Town,Nicholas D. Huntington,Laurent Bartholin,David K. Finlay,Mark J. Smyth,Mark J. Smyth,Thierry Walzer +22 more
TL;DR: The results suggest that boosting the metabolic activity of antitumor lymphocytes could be an effective strategy to promote immune-mediated tumor suppression and provide genetic, pharmacologic, and biochemical evidence that the kinase mTOR is a crucial signaling integrator of pro- and anti-inflammatory cytokines in NK cells.
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Model-based assessment of the Role of Uneven Partitioning of Molecular Content on Heterogeneity and Regulation of Differentiation in CD8 T-cell Immune Responses
TL;DR: It is shown that immune response dynamics can be explained by the molecular-content heterogeneity generated by uneven partitioning at cell division, and that the degree of unevenness of molecular partitioning affects the outcome of the immune response and can promote the generation of memory cells.
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A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains
Michelle Simon,Simon Greenaway,Jacqueline K. White,Helmut Fuchs,Valerie Gailus-Durner,Sara Wells,Tania Sorg,Kim Wong,Elodie Bedu,Elizabeth J. Cartwright,Romain Dacquin,Sophia Djebali,Jeanne Estabel,Jochen Graw,Neil J. Ingham,Ian J. Jackson,Andreas Lengeling,Silvia Mandillo,Jacqueline Marvel,Hamid Meziane,Frédéric Preitner,Oliver Puk,Michel Roux,David J. Adams,Sarah Atkins,Abdel Ayadi,Lore Becker,Andrew Blake,Debra Brooker,Heather Cater,Marie-France Champy,Roy Combe,Petr Danecek,Armida Di Fenza,Hilary Gates,Anna-Karin Gerdin,Elisabetta Golini,John M. Hancock,Wolfgang Hans,Sabine M. Hölter,Tertius Hough,Pierre Jurdic,Thomas M. Keane,Hugh P. Morgan,Werner Müller,Frauke Neff,George Nicholson,Bastian Pasche,Laura-Anne Roberson,Jan Rozman,Mark Sanderson,Luis Santos,Mohammed Selloum,Carl Shannon,Anne Southwell,Glauco P. Tocchini-Valentini,Valerie E. Vancollie,Henrik Westerberg,Wolfgang Wurst,Min Zi,Binnaz Yalcin,Binnaz Yalcin,Ramiro Ramirez-Solis,Karen P. Steel,Ann-Marie Mallon,Martin Hrabě de Angelis,Yann Herault,Steve D.M. Brown +67 more
TL;DR: Comparison of C57BL/6J and C57bl/6N demonstrates a range of phenotypic differences that have the potential to impact upon penetrance and expressivity of mutational effects in these strains.