Showing papers by "Jacques Ferlay published in 2010"

Estimates of worldwide burden of cancer in 2008: GLOBOCAN 2008.

Abstract: Estimates of the worldwide incidence and mortality from 27 cancers in 2008 have been prepared for 182 countries as part of the GLOBOCAN series published by the International Agency for Research on Cancer. In this article, we present the results for 20 world regions, summarizing the global patterns for the eight most common cancers. Overall, an estimated 12.7 million new cancer cases and 7.6 million cancer deaths occur in 2008, with 56% of new cancer cases and 63% of the cancer deaths occurring in the less developed regions of the world. The most commonly diagnosed cancers worldwide are lung (1.61 million, 12.7% of the total), breast (1.38 million, 10.9%) and colorectal cancers (1.23 million, 9.7%). The most common causes of cancer death are lung cancer (1.38 million, 18.2% of the total), stomach cancer (738,000 deaths, 9.7%) and liver cancer (696,000 deaths, 9.2%). Cancer is neither rare anywhere in the world, nor mainly confined to high-resource countries. Striking differences in the patterns of cancer from region to region are observed.

NORDCAN - A Nordic tool for cancer information, planning, quality control and research

Abstract: The NORDCAN database and program (www.ancr.nu) include detailed information and results on cancer incidence, mortality and prevalence in each of the Nordic countries over fi ve decades and has lately been supplemented with predictions of cancer incidence and mortality; future extensions include the incorporation of cancer survival estimates. Material and methods . The data originates from the national cancer registries and causes of death registries in Denmark, Finland, Iceland, Norway, Sweden, and Faroe Islands and is regularly updated. Presently 41 cancer entities are included in the common dataset, and conversions of the original national data according to international rules ensure comparability. Results. With 25 million inhabitants in the Nordic countries, 130 000 incident cancers are reported yearly, alongside nearly 60 000 cancer deaths, with almost a million persons living with a cancer diagnosis. This web-based application is available in English and in each of the fi ve Nordic national languages. It includes comprehensive and easy-to-use descriptive epidemiology tools that provide tabulations and graphs, with further user-specifi ed options available. Discussion. The NORDCAN database aims to provide comparable and timely data to serve the varying needs of policy makers, cancer societies, the public, and journalists, as well as the clinical and research community.

Fifty years of cancer incidence: CI5 I-IX.

Abstract: The Cancer Incidence in Five Continents (CI5) series comprises nine volumes that bring together peer-reviewed results from population-based cancer registries worldwide. The aim of each is to make available comparable data on cancer incidence from as wide a range of geographical locations as possible. In addition, the existence of long time series of data allows the evolution of risk in different populations over time to be studied. The CI5 I-IX database brings together the results from all nine volumes, spanning a period of some 50 years. In addition, unpublished annual data, with more diagnostic detail, are made available for many cancer registries with 15 or more years of recent data. We describe the construction and composition of the CI5 databases, and provide examples of how they can be used to prepare tables and graphs comparing incidence rates between populations. This is the classical role of descriptive statistics: to allow formulation of hypotheses that might explain the observed differences (geographically, over time, in population subgroups) and that can be tested by further study. Such statistics are also essential components in the planning and evaluation of cancer control programmes.

Global Burden of Breast Cancer

Abstract: Breast cancer in women is a major public health problem throughout the world. It is the most common cancer among women both in developed and developing countries. One in ten of all new cancers diagnosed worldwide each year is a cancer of the female breast. It is also the principal cause of death from cancer among women globally. More than 1.1 million cases are diagnosed and more than 410,000 patients die of it worldwide (Ferlay et al. 2004). It is the second most common cancer now, after lung cancer, when ranked by cancer occurrence in both sexes. About 55% of the global burden is currently experienced in developed countries, but incidence rates are rapidly rising in developing countries. We review the global burden of breast cancer, focusing on patterns of disease in terms of incidence and mortality and their geographical and temporal variations in different regions of the world. We also discuss briefly the sources and methods of estimation, validity and completeness of available data, and possible explanations for the observed patterns of incidence and mortality.

Cancer in Asia - Incidence rates based on data in cancer incidence in five continents IX (1998-2002).

Abstract: Data from 44 cancer registries in 15 countries in Asia were published in Cancer Incidence in Five Continents Volume IX (CI5 IX). These and findings from 3 other registries were here analysed to provide an overview on the incidence and characteristics of specific cancers by country/region in Asia. Using the collected database, the annual number of cancer cases and the corresponding population numbers divided into six age groups (0-29, 30-39, 40-49, 50-59, 60-69, 70 and more) were extracted and used for incidence estimation. The incidence rates of cancer across Asia vary greatly, with approximately three fold differences in both males and females.

A comparison of two methods to estimate the cancer incidence and mortality burden in China in 2005.

Abstract: Knowledge of the cancer profile is an important step in planning rational cancer control programs and evaluation of their impact. Due to rapid changes in cancer incidence in China, national surveys may be insufficiently timely to provide adequate descriptions of the national burden. To evaluate the utility of cancer registries in describing the national cancer profile, this study compared two methods of estimating national cancer-specific incidence and mortality in China 2005, based on the Third National Death Survey (method I) as compared with registry material (method II). A total of 2.6 million cancer cases and 1.8 million cancer deaths were estimated by method I, as compared to 2.8 million cancer cases and 1.9 million cancer deaths using method II. The higher level of burden using the latter method in part may be due to a sizable differential in the magnitude of incidence rates across registries for certain cancer sites. Most cancer registries have been located in relatively more developed urban areas, or rural areas associated with higher risk for certain cancers. There are substantial differences in the cancer profile between urban and rural communities in China, and there may be concerns regarding the national representativeness of the data aggregated from this set of cancer registries. Timely and reliable estimation of cancer can only be realized if accurate information is available from cancer registries covering representative samples of the country.

Descriptive Epidemiology: International Patterns

Abstract: Head and neck cancers (HNC) are a group of neoplasms common in several regions of the world where the prevalence of tobacco habits and alcohol consumption in the population is high. These cancers accounted for 420,000 new cases among males and 142,000 incident cases among females in 2002 around the world (Table 1 ) [1] . They are responsible for 8% of male (257,779/3,092,119) and 4% of female cancers (101,654/2,735,386) in the developing world. In developed countries, they account for 6% of male (163,377/2,698,175) and 2% of female cancers (40,762/2,317,939). The incidence rate of HNC and the distribution of cancers in head and neck anatomical subsites vary greatly in different geographical regions. The variation in cancer distribution by subsites is most likely due to differences in the relative distribution of the known risk factors such as tobacco chewing, smoking, and alcohol consumption. Misclassification of subsites is also a possibility due to the difficulties in assigning the primary site of origin, especially due to the anatomical proximity between the various subsites (for example, cancers of the supraglottic larynx and hypopharynx). However, patterns of disease distribution provide valuable clues for disease prevention and control. We will review the global geographical distribution and trends in incidence and mortality of HNC.