Jacques Poisson

Bio: Jacques Poisson is an academic researcher from University of Paris. The author has contributed to research in topics: Cyanohydrin & Kinetic resolution. The author has an hindex of 16, co-authored 51 publications receiving 746 citations. Previous affiliations of Jacques Poisson include Centre national de la recherche scientifique.

Isolation of leishmanicidal triterpenes and lignans from the Amazonian liana Doliocarpus dentatus (Dilleniaceae)

Abstract: The in vitro antileishmanial activity of triterpenes and lignans of an Amazonian medicinal plant, Doliocarpus dentatus (Aublet) Standley, is reported for the first time against amastigotes of Leishmania amazonensis. Terpenes, for example, betulinic acid, betulin and betulinaldehyde were isolated by bioassay-linked extraction. The lignans were characterized as (+) pinoresinol, (+) medioresinol and (-) lirioresinol B.

A simple total synthesis of naturally occurring hydroxy-amino acids by enzymatic kinetic resolution

Abstract: Both optically pure enantiomers of GABOB and isoserine were obtained by enzymatic kinetic resolution of acetylated precursors in three or four steps. The key intermediates were cyanohydrins available from simple aldehydes. This procedure can be applied to other unusual hydroxy amino acids widely distributed in biologically important peptides.

Bioactivities, bioactive compounds and chemical constituents of mangrove plants

Abstract: This review article presents the traditional and medicinal uses, and examines recent investigations on the biological activities of extracts, and chemicals identified from mangroves and mangal associates. Metabolites identified from mangrove plants are classified according to ‘chemical classes’, and some of their structures are illustrated. The article also presents some of the functions of the chemicals present and attempt to emphasize and create an awareness of the great of potential mangroves and mangal associates possess as a source of novel agrochemicals, compounds of medicinal value, and a new source of many already known biologically active compounds.