J
Jacques R. Rouleau
Researcher at Laval University
Publications - 80
Citations - 9472
Jacques R. Rouleau is an academic researcher from Laval University. The author has contributed to research in topics: Myocardial infarction & Ejection fraction. The author has an hindex of 26, co-authored 72 publications receiving 9227 citations. Previous affiliations of Jacques R. Rouleau include Brigham and Women's Hospital & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. results of the survival and ventricular enlargement trial
Marc A. Pfeffer,Eugene Braunwald,Lemuel A. Moyé,Lofty L. Basta,Edward J. Brown,Thomas E. Cuddy,Barry R. Davis,Edward M. Geltman,Steven Goldman,Greg C. Flaker,Marc Klein,Gervasio A. Lamas,Milton Packer,Jacques R. Rouleau,Jean L. Rouleau,John D. Rutherford,John H. Wertheimer,C. Morton Hawkins +17 more
TL;DR: In patients with asymptomatic left ventricular dysfunction after myocardial infarction, long-term administration of captopril was associated with an improvement in survival and reduced morbidity and mortality due to major cardiovascular events.
Journal ArticleDOI
Cardiovascular death and left ventricular remodeling two years after myocardial infarction: baseline predictors and impact of long-term use of captopril: information from the Survival and Ventricular Enlargement (SAVE) trial.
Martin St. John Sutton,Marc A. Pfeffer,Lemuel A. Moyé,Ted Plappert,Jean L. Rouleau,Gervasio A. Lamas,Jacques R. Rouleau,John O. Parker,Malcolm Arnold,Bruce Sussex,Eugene Braunwald +10 more
TL;DR: LV dilatation is progressive, associated with chamber distortion and deteriorating function that is unaffected by captopril beyond 1 year, and occurred in >50% of patients by 2 years.
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Thallium-201 myocardial perfusion imaging at rest and during exercise. Comparative sensitivity to electrocardiography in coronary artery disease.
TL;DR: Exercise thallium-201 MPI is a useful adjunct to conventional exercise testing particularly when evaluating patients with abnormal resting ECGs, those who develop ventricular conduction defects or arrhythmias during exercise, and those who fail to achieve their predicted heart rate because of fatigue or breathlessness.
Journal ArticleDOI
Right ventricular dysfunction and risk of heart failure and mortality after myocardial infarction
Leonardo A. M. Zornoff,Hicham Skali,Marc A. Pfeffer,Martin St. John Sutton,Jean L. Rouleau,Gervasio A. Lamas,Ted Plappert,Jacques R. Rouleau,Jacques R. Rouleau,Lemuel A. Moyé,Lemuel A. Moyé,Sandra J. Lewis,Eugene Braunwald,Scott D. Solomon,Save Investigators +14 more
TL;DR: Right ventricular function is an independent predictor of death and the development of HF in patients with LV dysfunction after MI, after adjusting for age, gender, diabetes mellitus, hypertension, previous MI, LVEF, infarct size, cigarette smoking and treatment assignment.
Journal ArticleDOI
Prognostic value of neurohumoral activation in patients with an acute myocardial infarction : effect of captopril
Jean L. Rouleau,Milton Packer,Lemuel A. Moyé,Jacques de Champlain,Daniel G. Bichet,Marc Klein,Jacques R. Rouleau,Bruce Sussex,J. Malcolm O. Arnold,Francois Sestier,John O. Parker,Patricia McEwan,Victoria Bernstein,T. Edward Cuddy,Gervasio A. Lamas,Stephen S. Gottlieb,John McCans,Claude Nadeau,François Delage,Chuan Chuan C Wun,Marc A. Pfeffer +20 more
TL;DR: Only plasma renin activity and aldosterone, atrial natriuretic peptide and arginine vasopressin were independent predictors of the combined end points of cardiovascular mortality, development of severe heart failure or recurrent myocardial infarction.