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Jae U. Jung

Researcher at University of Southern California

Publications -  297
Citations -  31955

Jae U. Jung is an academic researcher from University of Southern California. The author has contributed to research in topics: Kaposi's sarcoma-associated herpesvirus & Signal transduction. The author has an hindex of 76, co-authored 279 publications receiving 28536 citations. Previous affiliations of Jae U. Jung include Cleveland Clinic Lerner Research Institute & Pusan National University.

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Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky, +2522 more
- 21 Jan 2016 - 
TL;DR: In this paper, the authors present a set of guidelines for the selection and interpretation of methods for use by investigators who aim to examine macro-autophagy and related processes, as well as for reviewers who need to provide realistic and reasonable critiques of papers that are focused on these processes.
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Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

Daniel J. Klionsky, +235 more
- 16 Feb 2008 - 
TL;DR: A set of guidelines for the selection and interpretation of the methods that can be used by investigators who are attempting to examine macroautophagy and related processes, as well as by reviewers who need to provide realistic and reasonable critiques of papers that investigate these processes are presented.
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TRIM25 RING-finger E3 ubiquitin ligase is essential for RIG-I-mediated antiviral activity

TL;DR: It is demonstrated that TRIM25 E3 ubiquitin ligase induces the Lys 63-linked ubiquitination of RIG-I, which is crucial for the cytosolic Rig-I signalling pathway to elicit host antiviral innate immunity.
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Autophagic and tumour suppressor activity of a novel Beclin1-binding protein UVRAG

TL;DR: UVRAG is identified as an essential component of the Beclin1–PI(3)KC3 lipid kinase complex that is an important signalling checkpoint for autophagy and tumour-cell growth.
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Bif-1 interacts with Beclin 1 through UVRAG and regulates autophagy and tumorigenesis.

TL;DR: It is demonstrated that Bif-1 interacts with Beclin 1 through ultraviolet irradiation resistance-associated gene (UVRAG) and functions as a positive mediator of the class III PI(3) kinase (PI( 3)KC3) and observed that B if-1 ablation prolongs cell survival under starvation conditions.