J
Jaime Huerta-Cepas
Researcher at Technical University of Madrid
Publications - 75
Citations - 36335
Jaime Huerta-Cepas is an academic researcher from Technical University of Madrid. The author has contributed to research in topics: Genome & Phylogenetic tree. The author has an hindex of 39, co-authored 64 publications receiving 23644 citations. Previous affiliations of Jaime Huerta-Cepas include European Bioinformatics Institute & Pompeu Fabra University.
Papers
More filters
Journal ArticleDOI
STRING v11: protein-protein association networks with increased coverage, supporting functional discovery in genome-wide experimental datasets.
Damian Szklarczyk,Annika L. Gable,David Lyon,Alexander Junge,Stefan Wyder,Jaime Huerta-Cepas,Milan Simonovic,Nadezhda Tsankova Doncheva,John H. Morris,Peer Bork,Lars Juhl Jensen,Christian von Mering +11 more
TL;DR: The latest version of STRING more than doubles the number of organisms it covers, and offers an option to upload entire, genome-wide datasets as input, allowing users to visualize subsets as interaction networks and to perform gene-set enrichment analysis on the entire input.
Journal ArticleDOI
STRING v10: protein–protein interaction networks, integrated over the tree of life
Damian Szklarczyk,Andrea Franceschini,Stefan Wyder,Kristoffer Forslund,Davide Heller,Jaime Huerta-Cepas,Milan Simonovic,Alexander Roth,Alberto Santos,Kalliopi Tsafou,Michael Kuhn,Peer Bork,Lars Juhl Jensen,Christian von Mering +13 more
TL;DR: H hierarchical and self-consistent orthology annotations are introduced for all interacting proteins, grouping the proteins into families at various levels of phylogenetic resolution in the STRING database.
Journal ArticleDOI
eggNOG 5.0: a hierarchical, functionally and phylogenetically annotated orthology resource based on 5090 organisms and 2502 viruses.
Jaime Huerta-Cepas,Damian Szklarczyk,Davide Heller,Ana Hernández-Plaza,Sofia K. Forslund,Helen Cook,Daniel R. Mende,Ivica Letunic,Thomas Rattei,Lars Juhl Jensen,Christian von Mering,Peer Bork +11 more
TL;DR: eggNOG as discussed by the authors is a public database of orthology relationships, gene evolutionary histories and functional annotations, with a major update of the underlying genome sets, which have been expanded to 4445 representative bacteria and 168 archaea derived from 25 038 genomes.
Journal ArticleDOI
Fast Genome-Wide Functional Annotation through Orthology Assignment by eggNOG-Mapper
Jaime Huerta-Cepas,Kristoffer Forslund,Luis Pedro Coelho,Damian Szklarczyk,Damian Szklarczyk,Lars Juhl Jensen,Christian von Mering,Christian von Mering,Peer Bork +8 more
TL;DR: EggNOG-mapper is developed, a tool for functional annotation of large sets of sequences based on fast orthology assignments using precomputed clusters and phylogenies from the eggNOG database, and scored within the top-5 methods in the three GO categories using the CAFA2 NK-partial benchmark.
Journal ArticleDOI
Whole-genome analyses resolve early branches in the tree of life of modern birds
Erich D. Jarvis,Siavash Mirarab,Andre J. Aberer,Bo Li,Bo Li,Bo Li,Peter Houde,Cai Li,Cai Li,Simon Y. W. Ho,Brant C. Faircloth,Benoit Nabholz,Jason T. Howard,Alexander Suh,Claudia C. Weber,Rute R. da Fonseca,Jianwen Li,Fang Zhang Zhang,Hui Li,Long Zhou,Nitish Narula,Nitish Narula,Liang Liu,Ganesh Ganapathy,Bastien Boussau,Shamsuzzoha Bayzid,Volodymyr Zavidovych,Sankar Subramanian,Toni Gabaldón,Salvador Capella-Gutierrez,Jaime Huerta-Cepas,Bhanu Rekepalli,Bhanu Rekepalli,Kasper Munch,Mikkel H. Schierup,Bent E. K. Lindow,Wesley C. Warren,David A. Ray,Richard E. Green,Michael William Bruford,Xiangjiang Zhan,Xiangjiang Zhan,Andrew Dixon,Shengbin Li,Ning Li,Yinhua Huang,Elizabeth P. Derryberry,Elizabeth P. Derryberry,Mads F. Bertelsen,Frederick H. Sheldon,Robb T. Brumfield,Claudio V. Mello,Claudio V. Mello,Peter V. Lovell,Morgan Wirthlin,Maria Paula Cruz Schneider,Francisco Prosdocimi,José Alfredo Samaniego,Amhed Missael Vargas Velazquez,Alonzo Alfaro-Núñez,Paula F. Campos,Bent O. Petersen,Thomas Sicheritz-Pontén,An Pas,Thomas L. Bailey,R. Paul Scofield,Michael Bunce,David M. Lambert,Qi Zhou,Polina L. Perelman,Amy C. Driskell,Beth Shapiro,Zijun Xiong,Yongli Zeng,Shiping Liu,Zhenyu Li,Binghang Liu,Kui Wu,Jin Xiao,Xiong Yinqi,Quiemei Zheng,Yong Zhang,Huanming Yang,Jian Wang,Linnéa Smeds,Frank E. Rheindt,Michael J. Braun,Jon Fjeldså,Ludovic Orlando,F. Keith Barker,Knud A. Jønsson,Warren E. Johnson,Klaus-Peter Koepfli,Stephen J. O'Brien,David Haussler,Oliver A. Ryder,Carsten Rahbek,Eske Willerslev,Gary R. Graves,Gary R. Graves,Travis C. Glenn,John E. McCormack,Dave Burt,Hans Ellegren,Per Alström,Scott V. Edwards,Alexandros Stamatakis,David P. Mindell,Joel Cracraft,Edward L. Braun,Tandy Warnow,Tandy Warnow,Wang Jun,M. Thomas P. Gilbert,M. Thomas P. Gilbert,Guojie Zhang,Guojie Zhang +116 more
TL;DR: A genome-scale phylogenetic analysis of 48 species representing all orders of Neoaves recovered a highly resolved tree that confirms previously controversial sister or close relationships and identifies the first divergence in Neoaves, two groups the authors named Passerea and Columbea.